Adenosine A1 Receptor

Known as: ADORA1, Receptor, Adenosine A1, Adenosine A1 Receptors 
A subtype of ADENOSINE RECEPTOR that is found expressed in a variety of tissues including the BRAIN and DORSAL HORN NEURONS. The receptor is… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2018
05019822018

Related topics

Related topics

20 relations
ADORA1 geneBlood CirculationG Protein-Coupled Receptor GenesG Protein-Coupled Receptor Signaling
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Broader (1)

Purinoceptor

Related mentions per year

Related mentions per year

1936-2019
19401960198020002020
Adenosine A1 Receptor
physiological aspects
Signal Transduction
inflammatory response
Blood Circulation
Phagocytosis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Mechanisms of Cisplatin-Induced Ototoxicity and Otoprotection
Evidence of significant hearing loss during the early days of use of cisplatin as a chemotherapeutic agent in cancer patients has… (More)
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Review
2017
Review
2017
Adenosine A1 and A2A Receptors in the Brain: Current Research and Their Role in Neurodegeneration.
The inhibitory adenosine A1 receptor (A1R) and excitatory A2A receptor (A2AR) are predominantly expressed in the brain. Whereas… (More)
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Highly Cited
2010
Highly Cited
2010
Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture
Acupuncture is an invasive procedure commonly used to relieve pain. Acupuncture is practiced worldwide, despite difficulties in… (More)
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Highly Cited
2006
Highly Cited
2006
Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1-A2A receptor heteromers.
The functional role of heteromers of G-protein-coupled receptors is a matter of debate. In the present study, we demonstrate that… (More)
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Highly Cited
2005
Highly Cited
2005
Neuroprotection by adenosine in the brain: From A1 receptor activation to A2A receptor blockade
Adenosine is a neuromodulator that operates via the most abundant inhibitory adenosine A1 receptors (A1Rs) and the less abundant… (More)
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Highly Cited
2001
Highly Cited
2001
Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptor.
Caffeine is believed to act by blocking adenosine A(1) and A(2A) receptors (A(1)R, A(2A)R), indicating that some A(1) receptors… (More)
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Highly Cited
2001
Highly Cited
2001
Abolished tubuloglomerular feedback and increased plasma renin in adenosine A1 receptor-deficient mice.
The hypothesis that adenosine acting on adenosine A1 receptors (A1R) regulates several renal functions and mediates… (More)
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Highly Cited
2000
Highly Cited
2000
Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes.
The possible molecular basis for the previously described antagonistic interactions between adenosine A(1) receptors (A(1)R) and… (More)
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Highly Cited
1995
Highly Cited
1995
Essential role of adenosine, adenosine A1 receptors, and ATP-sensitive K+ channels in cerebral ischemic preconditioning.
Preconditioning with sublethal ischemia protects against neuronal damage after subsequent lethal ischemic insults in hippocampal… (More)
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Highly Cited
1992
Highly Cited
1992
Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors.
We have recently demonstrated that human neutrophils (PMN) possess two different classes of adenosine receptors (A1 and A2) that… (More)
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