Acetyl-CoA Carboxylase 1

Known as: ACC-Alpha, ACACA, Acetyl-Coenzyme A Carboxylase Alpha 
Acetyl-CoA carboxylase 1 (2346 aa, ~266 kDa) is encoded by the human ACACA gene. This protein plays a role in the modulation of long-chain fatty acid… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2018
0204019802018

Papers overview

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2012
2012
Invadopodia are membrane protrusions that facilitate matrix degradation and cellular invasion. Although lipids have been… (More)
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Highly Cited
2012
Highly Cited
2012
Overcoming metabolic stress is a critical step for solid tumour growth. However, the underlying mechanisms of cell death and… (More)
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2008
Highly Cited
2008
www.sciencemag.org (this information is current as of August 7, 2008 ): The following resources related to this article are… (More)
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2006
Highly Cited
2006
Hepatic steatosis is a core feature of the metabolic syndrome and type 2 diabetes and leads to hepatic insulin resistance… (More)
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Highly Cited
2005
Highly Cited
2005
Acetyl-CoA carboxylases (ACC1 and ACC2) catalyze the carboxylation of acetyl-CoA to form malonyl-CoA, an intermediate metabolite… (More)
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2003
Highly Cited
2003
Acetyl-CoA carboxylase (ACCase) catalyses the carboxylation of acetyl-CoA, forming malonyl-CoA, which is used in the plastid for… (More)
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Highly Cited
2003
Highly Cited
2003
Malonyl-CoA, generated by acetyl-CoA carboxylases ACC1 and ACC2, is a key metabolite in the control of fatty acid synthesis and… (More)
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Highly Cited
2000
Highly Cited
2000
Animals, including humans, express two isoforms of acetyl-CoA carboxylase (EC ), ACC1 (M(r) = 265 kDa) and ACC2 (M(r) = 280 kDa… (More)
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Highly Cited
1997
Highly Cited
1997
cDNA encoding the 280-kDa acetyl-CoA carboxylase 2 (ACC2) isoform was isolated from human liver using the polymerase chain… (More)
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1996
Highly Cited
1996
The conditional mRNA transport mutant of Saccharomyces cerevisiae, acc1-7-1 (mtr7-1), displays a unique alteration of the nuclear… (More)
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