FAQ

Acetoxyacetylaminofluorene

Known as: N-Acetoxy-N-acetyl-2-aminofluorene, N Acetoxy 2 acetylaminofluorene, Acetamide, N-(acetyloxy)-N-9H-fluoren-2-yl- 
An alkylating agent that forms DNA ADDUCTS at the C-8 position in GUANINE, resulting in single strand breaks. It has demonstrated carcinogenic action… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1949-2018
0102019492017

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8 relations

Broader (1)

Alkylating Agents
In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Acetoxyacetylaminofluorene
In Blood
Alkylating Agents
chemical synthesis
standards characteristics
antagonists & inhibitors

Papers overview

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2002
2002
Involvement of mouse Rev3 in tolerance of endogenous and exogenous DNA damage.
The Rev3 gene of Saccharomyces cerevisiae encodes the catalytic subunit of DNA polymerase zeta that is implicated in mutagenic… (More)
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1998
1998
Carcinogens preferentially bind at methylated CpG in the p53 mutational hot spots.
The major mutational hot spots in human cancers occur at CpG sequences in the p53 gene. It is generally presumed that the… (More)
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1997
1997
Role and mechanisms of action of acetylcholine in the regulation of rat cholangiocyte secretory functions.
UNLABELLED We investigated, in isolated bile duct units (IBDU) and cholangiocytes isolated from normal rat liver, the occurrence… (More)
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1984
1984
2-Acetylaminofluorene-modified probes for the indirect hybridocytochemical detection of specific nucleic acid sequences.
A new approach is presented for the indirect hybridocytochemical localization of specific nucleic acid sequences in microscopic… (More)
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Highly Cited
1983
Highly Cited
1983
Base substitution mutations induced by metabolically activated aflatoxin B1.
We have determined the base substitutions generated by metabolically activated aflatoxin B1 in the lacI gene of a uvrB- strain of… (More)
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Highly Cited
1982
Highly Cited
1982
32P-postlabeling analysis of non-radioactive aromatic carcinogen--DNA adducts.
A newly developed enzymatic 32P-postlabeling method was applied to the analysis of DNA's containing non-radioactive arylamine… (More)
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1979
1979
Tumor initiators and promoters in the induction of Epstein-Barr virus.
The effect of various tumor initiators and promoters on induction of persisting Epstein-Barr virus (EBV) in different lines of… (More)
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1976
1976
DNA excision-repair deficiency of human peripheral blood lymphocytes treated with chemical carcinogens.
Human peripheral blood lymphocytes stimulated with concanavalin A for 72 hr have a 10-fold greater capacity to repair DNA damage… (More)
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1975
1975
Mutagenicity of carcinogenic azo dyes and their derivatives.
The mutagenicity of N,N-dimethyl-4-aminoazobenzene and N-methyl-4-aminoazobenzene and their derivatives was shown on Salmonella… (More)
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1971
1971
Studies on DNA repair in human lymphocytes treated with proximate carcinogens and alkylating agents.
SUMMARY The incorporation of thymidmne into DNA by human peripheral blood lymphocytes after exposure to alkylating agents or… (More)
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