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Acetoxyacetylaminofluorene

Known as: N-Acetoxy-N-acetyl-2-aminofluorene, N Acetoxy 2 acetylaminofluorene, Acetamide, N-(acetyloxy)-N-9H-fluoren-2-yl- 
An alkylating agent that forms DNA ADDUCTS at the C-8 position in GUANINE, resulting in single strand breaks. It has demonstrated carcinogenic action… Expand
National Institutes of Health

Papers overview

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2010
2010
Cutaneous secretions of toad species are an important source of bufadienolides, compounds that exhibit interesting structural… Expand
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Highly Cited
2002
Highly Cited
2002
The Rev3 gene of Saccharomyces cerevisiae encodes the catalytic subunit of DNA polymerase zeta that is implicated in mutagenic… Expand
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Highly Cited
2000
Highly Cited
2000
In addition to ergosterol (I), 3 beta,5 alpha,6 beta-trihydroxyergosta-7,22-diene (II), 3 beta-hydroxy-ergosta-5-ene (III), 3-oxo… Expand
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Highly Cited
1998
Highly Cited
1998
The major mutational hot spots in human cancers occur at CpG sequences in the p53 gene. It is generally presumed that the… Expand
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Highly Cited
1989
Highly Cited
1989
We have found that a wide variety of DNA-damaging agents and heat shock increase fos RNA to different extents in Chinese hamster… Expand
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Highly Cited
1984
Highly Cited
1984
We have examined the distribution of individual adducts in repetitive DNA sequences of rat liver in vivo after a single dose of… Expand
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1984
1984
A new approach is presented for the indirect hybridocytochemical localization of specific nucleic acid sequences in microscopic… Expand
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Highly Cited
1982
Highly Cited
1982
A newly developed enzymatic 32P-postlabeling method was applied to the analysis of DNA's containing non-radioactive arylamine… Expand
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1981
1981
The ability to excise (repair) UV-induced pyrimidine dimers in Escherichia coli is not related to its ability to remove N-methyl… Expand
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Highly Cited
1975
Highly Cited
1975
The mutagenicity of N,N-dimethyl-4-aminoazobenzene and N-methyl-4-aminoazobenzene and their derivatives was shown on Salmonella… Expand
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