Acetoxyacetylaminofluorene

Known as: N-Acetoxy-N-acetyl-2-aminofluorene, N Acetoxy 2 acetylaminofluorene, Acetamide, N-(acetyloxy)-N-9H-fluoren-2-yl- 
An alkylating agent that forms DNA ADDUCTS at the C-8 position in GUANINE, resulting in single strand breaks. It has demonstrated carcinogenic action… (More)
National Institutes of Health

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Topic mentions per year

1949-2018
0102019492017

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2002
2002
The Rev3 gene of Saccharomyces cerevisiae encodes the catalytic subunit of DNA polymerase zeta that is implicated in mutagenic… (More)
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1998
1998
The major mutational hot spots in human cancers occur at CpG sequences in the p53 gene. It is generally presumed that the… (More)
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1997
1997
UNLABELLED We investigated, in isolated bile duct units (IBDU) and cholangiocytes isolated from normal rat liver, the occurrence… (More)
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1984
1984
A new approach is presented for the indirect hybridocytochemical localization of specific nucleic acid sequences in microscopic… (More)
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Highly Cited
1983
Highly Cited
1983
We have determined the base substitutions generated by metabolically activated aflatoxin B1 in the lacI gene of a uvrB- strain of… (More)
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Highly Cited
1982
Highly Cited
1982
A newly developed enzymatic 32P-postlabeling method was applied to the analysis of DNA's containing non-radioactive arylamine… (More)
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1979
1979
The effect of various tumor initiators and promoters on induction of persisting Epstein-Barr virus (EBV) in different lines of… (More)
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1976
1976
Human peripheral blood lymphocytes stimulated with concanavalin A for 72 hr have a 10-fold greater capacity to repair DNA damage… (More)
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1975
1975
The mutagenicity of N,N-dimethyl-4-aminoazobenzene and N-methyl-4-aminoazobenzene and their derivatives was shown on Salmonella… (More)
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1971
1971
SUMMARY The incorporation of thymidmne into DNA by human peripheral blood lymphocytes after exposure to alkylating agents or… (More)
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