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Acetoxyacetylaminofluorene
Known as:
N-Acetoxy-N-acetyl-2-aminofluorene
, N Acetoxy 2 acetylaminofluorene
, Acetamide, N-(acetyloxy)-N-9H-fluoren-2-yl-
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An alkylating agent that forms DNA ADDUCTS at the C-8 position in GUANINE, resulting in single strand breaks. It has demonstrated carcinogenic action…
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National Institutes of Health
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Related topics
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8 relations
Broader (1)
Alkylating Agents
In Blood
agonists
analogs & derivatives
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Gold(I) catalyzed isomerization of 5-en-2-yn-1-yl acetates: an efficient access to acetoxy bicyclo[3.1.0]hexenes and 2-cycloalken-1-ones.
A. Buzas
,
F. Gagosz
Journal of the American Chemical Society
2006
Corpus ID: 30249178
The gold(I) catalyzed rearrangement of 5-en-2-yn-1-yl acetates into functionalized acetoxy bicyclo[3.1.0]hexenes is described…
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Highly Cited
2000
Highly Cited
2000
New bioactive metabolites produced by Colletotrichum sp., an endophytic fungus in Artemisia annua
Hong Lu
,
W. Zou
,
J. Meng
,
Jun Hu
,
R. Tan
2000
Corpus ID: 73549629
Highly Cited
1998
Highly Cited
1998
Carcinogens preferentially bind at methylated CpG in the p53 mutational hot spots.
J. X. Chen
,
Y. Zheng
,
M. West
,
M. Tang
Cancer research
1998
Corpus ID: 2932972
The major mutational hot spots in human cancers occur at CpG sequences in the p53 gene. It is generally presumed that the…
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Highly Cited
1989
Highly Cited
1989
Induction of fos RNA by DNA-damaging agents.
M. C. Hollander
,
A. Fornace
Cancer research
1989
Corpus ID: 38822270
We have found that a wide variety of DNA-damaging agents and heat shock increase fos RNA to different extents in Chinese hamster…
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Highly Cited
1986
Highly Cited
1986
Mutations activating human c-Ha-ras1 protooncogene (HRAS1) induced by chemical carcinogens and depurination.
K. Vousden
,
J. Bos
,
C. Marshall
,
D. Phillips
Proceedings of the National Academy of Sciences…
1986
Corpus ID: 29892965
In vitro modification of plasmids containing the human c-Ha-ras1 protooncogene (HRAS1) with the ultimate carcinogens N-acetoxy-2…
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Highly Cited
1984
Highly Cited
1984
Nonrandom binding of the carcinogen N-hydroxy-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo.
R. Gupta
Proceedings of the National Academy of Sciences…
1984
Corpus ID: 22483575
We have examined the distribution of individual adducts in repetitive DNA sequences of rat liver in vivo after a single dose of…
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Highly Cited
1984
Highly Cited
1984
2-Acetylaminofluorene-modified probes for the indirect hybridocytochemical detection of specific nucleic acid sequences.
J. Landegent
,
N. Jasen in de Wal
,
R. Baan
,
J. Hoeijmakers
,
M. van der Ploeg
Experimental cell research
1984
Corpus ID: 40290122
Highly Cited
1982
Highly Cited
1982
32P-postlabeling analysis of non-radioactive aromatic carcinogen--DNA adducts.
R. Gupta
,
M. V. Reddy
,
K. Randerath
Carcinogenesis
1982
Corpus ID: 26612542
A newly developed enzymatic 32P-postlabeling method was applied to the analysis of DNA's containing non-radioactive arylamine…
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Highly Cited
1981
Highly Cited
1981
Removal of O6-methylguanine from DNA of normal and xeroderma pigmentosum-derived lymphoblastoid lines
R. Sklar
,
B. Strauss
Nature
1981
Corpus ID: 4341155
The ability to excise (repair) UV-induced pyrimidine dimers in Escherichia coli is not related to its ability to remove N-methyl…
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Highly Cited
1975
Highly Cited
1975
Mutagenicity of carcinogenic azo dyes and their derivatives.
T. Yahagi
,
M. Degawa
,
Y. Seino
,
T. Matsushima
,
M. Nagao
Cancer letters
1975
Corpus ID: 21005917
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