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Acetoxyacetylaminofluorene

Known as: N-Acetoxy-N-acetyl-2-aminofluorene, N Acetoxy 2 acetylaminofluorene, Acetamide, N-(acetyloxy)-N-9H-fluoren-2-yl- 
An alkylating agent that forms DNA ADDUCTS at the C-8 position in GUANINE, resulting in single strand breaks. It has demonstrated carcinogenic action… 
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
The gold(I) catalyzed rearrangement of 5-en-2-yn-1-yl acetates into functionalized acetoxy bicyclo[3.1.0]hexenes is described… 
Highly Cited
1998
Highly Cited
1998
The major mutational hot spots in human cancers occur at CpG sequences in the p53 gene. It is generally presumed that the… 
Highly Cited
1989
Highly Cited
1989
We have found that a wide variety of DNA-damaging agents and heat shock increase fos RNA to different extents in Chinese hamster… 
Highly Cited
1986
Highly Cited
1986
In vitro modification of plasmids containing the human c-Ha-ras1 protooncogene (HRAS1) with the ultimate carcinogens N-acetoxy-2… 
Highly Cited
1984
Highly Cited
1984
  • R. Gupta
  • Proceedings of the National Academy of Sciences…
  • 1984
  • Corpus ID: 22483575
We have examined the distribution of individual adducts in repetitive DNA sequences of rat liver in vivo after a single dose of… 
Highly Cited
1982
Highly Cited
1982
A newly developed enzymatic 32P-postlabeling method was applied to the analysis of DNA's containing non-radioactive arylamine… 
Highly Cited
1981
Highly Cited
1981
The ability to excise (repair) UV-induced pyrimidine dimers in Escherichia coli is not related to its ability to remove N-methyl… 
Highly Cited
1975