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Acenocoumarol

Known as: 3-(alpha-Acetonyl-P-nitrobenzyl)-4-hydroxycoumarin, Acenocoumarol [Chemical/Ingredient], Nitrophenylacetylethyl-4-hydroxycoumarine 
A 4-hydroxycoumarin derivative with anticoagulant activity. As a vitamin K antagonist, acenocoumarol inhibits vitamin K epoxide reductase, thereby… 
National Institutes of Health

Related topics

Related topics

15 relations
Acenocoumarol:MCnc:Pt:Ser/Plas:QnAcenocoumarol:MCnt:Pt:Hair:QnIn Bloodagonists

Broader (1)

Anticoagulants

Narrower (5)

SinthromeSintromSyncoumarSyncumar

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
The use of rivaroxaban in patients with antiphospholipid syndrome: A series of 12 cases.
2008
2008
Comparison of INR stability between self-monitoring and standard laboratory method: preliminary results of a prospective study in 67 mechanical heart valve patients.
2008
2008
Elevated D-dimer concentration identifies patients with incomplete recanalization of pulmonary artery thromboemboli despite 6 months anticoagulation after the first episode of acute pulmonary…
2007
2007
Pharmacogenetics of acenocoumarol: CYP2C9, CYP2C19, CYP1A2, CYP3A4, CYP3A5 and ABCB1 gene polymorphisms and dose requirements
Background and objective:  Acenocoumarol (AC) is a coumarin derivative, vitamin K antagonist anticoagulant drug. It has a narrow… 
Highly Cited
2004
Highly Cited
2004
The risk of overanticoagulation in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon.
Cytochrome P4502C9 (CYP2C9) is the main enzyme implicated in coumarin anticoagulant metabolism. The variant alleles CYP2C9*2 and… 
Highly Cited
2001
Highly Cited
2001
Altered pharmacokinetics of R‐ and S‐acenocoumarol in a subject heterozygous for CYP2C9*3
Our objective was to study the pharmacokinetics of R‐ and S‐acenocoumarol in a subject who was highly sensitive to the… 
Highly Cited
2000
Highly Cited
2000
Bleeding risk factors in chronic oral anticoagulation with acenocoumarol
We studied major bleeding complications, death related to hemorrhage, and tried to identify predisposing factors for bleeding in… 
1998
1998
Detection of 4-hydroxycoumarin anticoagulants and their metabolites in urine as part of a systematic toxicological analysis procedure for acidic drugs and poisons by gas chromatography-mass…
1989
1989
The in vitro ketone reduction of warfarin and analogues. Substrate stereoselectivity, product stereoselectivity and species differences.
1974
1974
Low-dose subcutaneous heparin versus oral anticoagulants in the prevention of postoperative deep-venous thrombosis. A controlled clinical trial.
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