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Acenocoumarol
Known as:
3-(alpha-Acetonyl-P-nitrobenzyl)-4-hydroxycoumarin
, Acenocoumarol [Chemical/Ingredient]
, Nitrophenylacetylethyl-4-hydroxycoumarine
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A 4-hydroxycoumarin derivative with anticoagulant activity. As a vitamin K antagonist, acenocoumarol inhibits vitamin K epoxide reductase, thereby…
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National Institutes of Health
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Related topics
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15 relations
Acenocoumarol:MCnc:Pt:Ser/Plas:Qn
Acenocoumarol:MCnt:Pt:Hair:Qn
In Blood
agonists
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Broader (1)
Anticoagulants
Narrower (5)
Sinthrome
Sintrom
Syncoumar
Syncumar
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
The use of rivaroxaban in patients with antiphospholipid syndrome: A series of 12 cases.
Maksim Son
,
E. Wypasek
,
M. Celińska-Lowenhoff
,
A. Undas
Thrombosis Research
2015
Corpus ID: 205382241
2008
2008
Comparison of INR stability between self-monitoring and standard laboratory method: preliminary results of a prospective study in 67 mechanical heart valve patients.
C. Dauphin
,
B. Legault
,
+9 authors
C. de Riberolles
Archives of Cardiovascular Diseases
2008
Corpus ID: 44380269
2008
2008
Elevated D-dimer concentration identifies patients with incomplete recanalization of pulmonary artery thromboemboli despite 6 months anticoagulation after the first episode of acute pulmonary…
A. Kaczyńska
,
M. Kostrubiec
,
R. Pacho
,
J. Kunikowska
,
P. Pruszczyk
Thrombosis Research
2008
Corpus ID: 24394773
2007
2007
Pharmacogenetics of acenocoumarol: CYP2C9, CYP2C19, CYP1A2, CYP3A4, CYP3A5 and ABCB1 gene polymorphisms and dose requirements
R. B. Saraeva
,
I. Paskaleva
,
E. Doncheva
,
C. Eap
,
V. Ganev
Journal of Clinical Pharmacy and Therapeutics
2007
Corpus ID: 30620594
Background and objective: Acenocoumarol (AC) is a coumarin derivative, vitamin K antagonist anticoagulant drug. It has a narrow…
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Highly Cited
2004
Highly Cited
2004
The risk of overanticoagulation in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon.
L. Visser
,
M. V. van Vliet
,
+6 authors
B. H. Stricker
Pharmacogenetics (London)
2004
Corpus ID: 6390536
Cytochrome P4502C9 (CYP2C9) is the main enzyme implicated in coumarin anticoagulant metabolism. The variant alleles CYP2C9*2 and…
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Highly Cited
2001
Highly Cited
2001
Altered pharmacokinetics of R‐ and S‐acenocoumarol in a subject heterozygous for CYP2C9*3
H. Thijssen
,
M. Drittij
,
L. Vervoort
,
Johanna C. Vries‐Hanje
Clinical pharmacology and therapy
2001
Corpus ID: 25787505
Our objective was to study the pharmacokinetics of R‐ and S‐acenocoumarol in a subject who was highly sensitive to the…
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Highly Cited
2000
Highly Cited
2000
Bleeding risk factors in chronic oral anticoagulation with acenocoumarol
P. Casais
,
Analía Sánchez Luceros
,
S. Meschengieser
,
C. Fondevila
,
M. Santarelli
,
M. Lazzari
American journal of hematology/oncology
2000
Corpus ID: 44930834
We studied major bleeding complications, death related to hemorrhage, and tried to identify predisposing factors for bleeding in…
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1998
1998
Detection of 4-hydroxycoumarin anticoagulants and their metabolites in urine as part of a systematic toxicological analysis procedure for acidic drugs and poisons by gas chromatography-mass…
H. Maurer
,
J. W. Arlt
Journal of Chromatography B: Biomedical Sciences…
1998
Corpus ID: 1015159
1989
1989
The in vitro ketone reduction of warfarin and analogues. Substrate stereoselectivity, product stereoselectivity and species differences.
J. Hermans
,
H. Thijssen
Biochemical Pharmacology
1989
Corpus ID: 10267477
1974
1974
Low-dose subcutaneous heparin versus oral anticoagulants in the prevention of postoperative deep-venous thrombosis. A controlled clinical trial.
T.T.M.V. Van Vroonhoven
,
J. V. Zijl
,
H. Muller
The Lancet
1974
Corpus ID: 25319884
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