Ac-aspartyl-glutamyl-valyl-aspartyl-aminomethylcoumarin

Known as: Ac-DEVD-AMC, N-acetyl Asp-Glu-Val-Asp-7-amino-4-methylcoumarin, acetyl-DEVD-AMC 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
012319972017

Papers overview

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2017
2017
Thioridazine is known to have anti-tumor effects by inhibiting PI3K/Akt signaling, which is an important signaling pathway in… (More)
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2014
2014
Targeted drug delivery to tumor cells with minimized side effects and real-time in situ monitoring of drug efficacy is highly… (More)
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2014
2014
A versatile gold nanoparticle-based multifunctional RB-DEVD-AuNP-DTP has been developed to induce the targeted apoptosis of… (More)
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2013
2013
OBJECTIVES Most chemotherapy agents cause tumor cell death primarily by the induction of apoptosis. The ability to noninvasively… (More)
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2001
2001
While caspases play an established role as intracellular executors of apoptosis, little is known about extracellular activities… (More)
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1998
1998
We have previously demonstrated abrogation of bile salt-induced apoptosis by cathepsin B inhibitors. However, caspases have been… (More)
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1998
1998
BACKGROUND & AIMS The epidermal growth factor receptor (EGFR) is under investigation as a therapeutic target for cancers. Colon… (More)
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Highly Cited
1997
Highly Cited
1997
Dissociated cerebellar granule cells maintained in medium containing 25 mM potassium undergo an apoptotic death when switched to… (More)
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Highly Cited
1997
Highly Cited
1997
Neuronal apoptosis occurs during nervous system development and after pathological insults to the adult nervous system… (More)
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Highly Cited
1997
Highly Cited
1997
Apoptotic signaling cascades converge in the activation of caspases (interleukin-1beta converting enzyme like proteases… (More)
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