FAQ

Ac-aspartyl-glutamyl-valyl-aspartyl-aminomethylcoumarin

Known as: Ac-DEVD-AMC, N-acetyl Asp-Glu-Val-Asp-7-amino-4-methylcoumarin, acetyl-DEVD-AMC 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
012319972017

Related topics

Related topics

3 relations

Broader (3)

CoumarinsCysteine Proteinase InhibitorsOligopeptides

Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
Ac-aspartyl-glutamyl-valyl-aspartyl-aminomethylcoumarin
Oligopeptides
Coumarins
Cysteine Proteinase Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
NOX4-mediated ROS production induces apoptotic cell death via down-regulation of c-FLIP and Mcl-1 expression in combined treatment with thioridazine and curcumin
Thioridazine is known to have anti-tumor effects by inhibiting PI3K/Akt signaling, which is an important signaling pathway in… (More)
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2014
2014
Targeted theranostic platinum(IV) prodrug with a built-in aggregation-induced emission light-up apoptosis sensor for noninvasive early evaluation of its therapeutic responses in situ.
Targeted drug delivery to tumor cells with minimized side effects and real-time in situ monitoring of drug efficacy is highly… (More)
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2014
2014
Cancer-targeted functional gold nanoparticles for apoptosis induction and real-time imaging based on FRET.
A versatile gold nanoparticle-based multifunctional RB-DEVD-AuNP-DTP has been developed to induce the targeted apoptosis of… (More)
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2013
2013
Longitudinal Bioluminescence Imaging of the Dynamics of Doxorubicin Induced Apoptosis
OBJECTIVES Most chemotherapy agents cause tumor cell death primarily by the induction of apoptosis. The ability to noninvasively… (More)
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2001
2001
In vivo and in vitro evidence for extracellular caspase activity released from apoptotic cells.
While caspases play an established role as intracellular executors of apoptosis, little is known about extracellular activities… (More)
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1998
1998
Cystatin A expression reduces bile salt-induced apoptosis in a rat hepatoma cell line.
We have previously demonstrated abrogation of bile salt-induced apoptosis by cathepsin B inhibitors. However, caspases have been… (More)
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1998
1998
Inhibition of epidermal growth factor receptor kinase induces protease-dependent apoptosis in human colon cancer cells.
BACKGROUND & AIMS The epidermal growth factor receptor (EGFR) is under investigation as a therapeutic target for cancers. Colon… (More)
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Highly Cited
1997
Highly Cited
1997
Bax Deletion Further Orders the Cell Death Pathway in Cerebellar Granule Cells and Suggests a Caspase-independent Pathway to Cell Death
Dissociated cerebellar granule cells maintained in medium containing 25 mM potassium undergo an apoptotic death when switched to… (More)
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Highly Cited
1997
Highly Cited
1997
Activation of the CED3/ICE-related protease CPP32 in cerebellar granule neurons undergoing apoptosis but not necrosis.
Neuronal apoptosis occurs during nervous system development and after pathological insults to the adult nervous system… (More)
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Highly Cited
1997
Highly Cited
1997
Inhibition of caspase-3 by S-nitrosation and oxidation caused by nitric oxide.
Apoptotic signaling cascades converge in the activation of caspases (interleukin-1beta converting enzyme like proteases… (More)
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