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Ac-aspartyl-glutamyl-valyl-aspartyl-aminomethylcoumarin

Known as: Ac-DEVD-AMC, N-acetyl Asp-Glu-Val-Asp-7-amino-4-methylcoumarin, acetyl-DEVD-AMC 
 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

CoumarinsCysteine Proteinase InhibitorsOligopeptides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Single-step green synthesis and characterization of gold-conjugated polyphenol nanoparticles with antioxidant and biological activities
Background Gold nanoparticles (GNPs) are likely to provide an attractive platform for combining a variety of biophysicochemical… Expand
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2014
2014
Poly β-cyclodextrin/TPdye nanomicelle-based two-photon nanoprobe for caspase-3 activation imaging in live cells and tissues.
Two-photon excitation (TPE) with near-infrared (NIR) photons as the excitation source has important advantages over conventional… Expand
2013
2013
Longitudinal Bioluminescence Imaging of the Dynamics of Doxorubicin Induced Apoptosis
Objectives: Most chemotherapy agents cause tumor cell death primarily by the induction of apoptosis. The ability to noninvasively… Expand
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2012
2012
Self-assembled complex of probe peptide--E. Coli RNA I conjugate and nano graphene oxide for apoptosis diagnosis.
Caspase-3 plays an important role in the initiation and propagation of apoptosis which is involved in various kinds of diseases… Expand
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2010
2010
The execution phase of autophagy associated PCD during insect metamorphosis
During metamorphosis of Manduca sexta, involution of labial glands follows an autophagic pathway towards programmed cell death… Expand
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2009
2009
Real-Time Detection of Caspase-3-Like Protease Activation in Vivo Using Fluorescence Resonance Energy Transfer during Plant Programmed Cell Death Induced by Ultraviolet C Overexposure1[C]
Caspase-like proteases have been demonstrated to be involved in plant programmed cell death (PCD). Here, the time scale of… Expand
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Highly Cited
2008
Highly Cited
2008
DEVD‐NucView488: a novel class of enzyme substrates for real‐time detection of caspase‐3 activity in live cells
Live‐cell detection of intracellular enzyme activity requires that substrates are cell‐permeable and that the generated products… Expand
Highly Cited
1999
Highly Cited
1999
Inhibition of apoptosis and clonogenic survival of cells expressing crmA variants: optimal caspase substrates are not necessarily optimal inhibitors
To study the role of various caspases during apoptosis, we have designed a series of caspase inhibitors based on the cowpox virus… Expand
Highly Cited
1998
Highly Cited
1998
Inhibition of epidermal growth factor receptor kinase induces protease-dependent apoptosis in human colon cancer cells.
BACKGROUND & AIMS The epidermal growth factor receptor (EGFR) is under investigation as a therapeutic target for cancers. Colon… Expand
Highly Cited
1997
Highly Cited
1997
Activation of Multiple Interleukin-1β Converting Enzyme Homologues in Cytosol and Nuclei of HL-60 Cells during Etoposide-induced Apoptosis*
Recent genetic and biochemical studies have implicated cysteine-dependent aspartate-directed proteases (caspases) in the active… Expand
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