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Ac-aspartyl-glutamyl-valyl-aspartyl-aminomethylcoumarin
Known as:
Ac-DEVD-AMC
, N-acetyl Asp-Glu-Val-Asp-7-amino-4-methylcoumarin
, acetyl-DEVD-AMC
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (3)
Coumarins
Cysteine Proteinase Inhibitors
Oligopeptides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Rational design of caspase-responsive smart molecular probe for positron emission tomography imaging of drug-induced apoptosis
L. Qiu
,
Wei Wang
,
+7 authors
Jianguo Lin
Theranostics
2019
Corpus ID: 204846260
Purpose: Positron emission tomography (PET) imaging of apoptosis is very important for early evaluation of tumor therapeutic…
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Highly Cited
2014
Highly Cited
2014
Single-step green synthesis and characterization of gold-conjugated polyphenol nanoparticles with antioxidant and biological activities
V. Sanna
,
N. Pala
,
+7 authors
M. Sechi
International journal of nanomedicine
2014
Corpus ID: 4310943
Background Gold nanoparticles (GNPs) are likely to provide an attractive platform for combining a variety of biophysicochemical…
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2014
2014
Poly β-cyclodextrin/TPdye nanomicelle-based two-photon nanoprobe for caspase-3 activation imaging in live cells and tissues.
Huijuan Yan
,
Leiliang He
,
+4 authors
W. Tan
Analytical chemistry
2014
Corpus ID: 9638166
Two-photon excitation (TPE) with near-infrared (NIR) photons as the excitation source has important advantages over conventional…
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2013
2013
Longitudinal Bioluminescence Imaging of the Dynamics of Doxorubicin Induced Apoptosis
G. Niu
,
Lei Zhu
,
+7 authors
Xiaoyuan Chen
Theranostics
2013
Corpus ID: 15501304
Objectives: Most chemotherapy agents cause tumor cell death primarily by the induction of apoptosis. The ability to noninvasively…
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2010
2010
The execution phase of autophagy associated PCD during insect metamorphosis
C. Facey
,
R. Lockshin
Apoptosis
2010
Corpus ID: 22640750
During metamorphosis of Manduca sexta, involution of labial glands follows an autophagic pathway towards programmed cell death…
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Highly Cited
2009
Highly Cited
2009
Real-Time Detection of Caspase-3-Like Protease Activation in Vivo Using Fluorescence Resonance Energy Transfer during Plant Programmed Cell Death Induced by Ultraviolet C Overexposure1[C]
Lingrui Zhang
,
Qixian Xu
,
D. Xing
,
Caiji Gao
,
Hongwu Xiong
Plant Physiology
2009
Corpus ID: 25348890
Caspase-like proteases have been demonstrated to be involved in plant programmed cell death (PCD). Here, the time scale of…
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Highly Cited
2008
Highly Cited
2008
DEVD‐NucView488: a novel class of enzyme substrates for real‐time detection of caspase‐3 activity in live cells
Hui Cen
,
Fei Mao
,
I. Aronchik
,
Rholinelle Joy Fuentes
,
G. Firestone
FASEB journal : official publication of the…
2008
Corpus ID: 10515847
Live‐cell detection of intracellular enzyme activity requires that substrates are cell‐permeable and that the generated products…
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Highly Cited
1999
Highly Cited
1999
Inhibition of apoptosis and clonogenic survival of cells expressing crmA variants: optimal caspase substrates are not necessarily optimal inhibitors
P. Ekert
,
J. Silke
,
D. Vaux
The EMBO journal
1999
Corpus ID: 10546254
To study the role of various caspases during apoptosis, we have designed a series of caspase inhibitors based on the cowpox virus…
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Highly Cited
1998
Highly Cited
1998
Inhibition of epidermal growth factor receptor kinase induces protease-dependent apoptosis in human colon cancer cells.
W. Karnes
,
S. Weller
,
+4 authors
S. Kaufmann
Gastroenterology
1998
Corpus ID: 6219720
Highly Cited
1997
Highly Cited
1997
Activation of Multiple Interleukin-1β Converting Enzyme Homologues in Cytosol and Nuclei of HL-60 Cells during Etoposide-induced Apoptosis*
Luis M. Martins
,
T. Kottke
,
+12 authors
S. Kaufmann
The Journal of Biological Chemistry
1997
Corpus ID: 13936249
Recent genetic and biochemical studies have implicated cysteine-dependent aspartate-directed proteases (caspases) in the active…
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