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AZD 7009

Known as: AZD-7009, AZD7009 
 
National Institutes of Health

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Organic Chemicals

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Decrease of the atrial fibrillatory rate, increased organization of the atrial rhythm and termination of atrial fibrillation by AZD7009.
BACKGROUND The atrial fibrillatory rate (AFR), on AZD7009 as compared to placebo, was investigated as a potential biomarker for… Expand
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2012
2012
Enhancing crystalline properties of a cardiovascular active pharmaceutical ingredient using a process analytical technology based crystallization feedback control strategy.
Pharmaceutical regulatory bodies require minimal presence of solvent in an active pharmaceutical ingredient (API) after… Expand
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2009
2009
Rapid conversion of persistent atrial fibrillation to sinus rhythm by intravenous AZD7009.
This randomized, double-blind trial compared cardioversion rates between AZD7009 infusion (15-minute 3.25 mg/min, 15-minute 4.4… Expand
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2007
2007
Functional effects of the late sodium current inhibition by AZD7009 and lidocaine in rabbit isolated atrial and ventricular tissue and Purkinje fibre.
AZD7009 (tert-Butyl-2-(7-[(2S)-3-(4-cyanophenoxy)-2-hydroxypropyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl)ethylcarbamate) is an… Expand
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2006
2006
Safe and effective conversion of persistent atrial fibrillation to sinus rhythm by intravenous AZD7009.
BACKGROUND Acute drug conversion of persistent atrial fibrillation usually fails. OBJECTIVES The purpose of this study was to… Expand
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2006
2006
Characterization of the in vivo and in vitro electrophysiological effects of the novel antiarrhythmic agent AZD7009 in atrial and ventricular tissue of the dog.
This study evaluated the effects of the novel antiarrhythmic agent AZD7009 on atrial and ventricular repolarization and on the Na… Expand
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2006
2006
Electrophysiological and antiarrhythmic effects of the novel antiarrhythmic agent AZD7009: a comparison with azimilide and AVE0118 in the acutely dilated right atrium of the rabbit in vitro.
AIMS To compare the electrophysiological and antiarrhythmic effects of AZD7009, azimilide, and AVE0118 in the acutely dilated… Expand
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2005
2005
Blocking characteristics of hERG, hNav1.5, and hKvLQT1/hminK after administration of the novel anti-arrhythmic compound AZD7009.
INTRODUCTION AZD7009 is a novel anti-arrhythmic compound under development for short- and long-term management of atrial… Expand
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2005
2005
Assessment of the proarrhythmic potential of the novel antiarrhythmic agent AZD7009 and dofetilide in experimental models of torsades de pointes.
BACKGROUND This study examined the proarrhythmic potential of the novel antiarrhythmic agent AZD7009 and dofetilide. METHODS… Expand
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2004
2004
Azd7009: a new antiarrhythmic drug with predominant effects on the atria effectively terminates and prevents reinduction of atrial fibrillation and flutter in the sterile pericarditis model.
INTRODUCTION We tested the hypothesis that AZD7009 terminates induced atrial fibrillation (AF) and flutter (AFL) and prevents… Expand
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