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AY-9944

Known as: AY9944, A-7, AY9944, AY9944 A 7 
National Institutes of Health

Papers overview

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2006
2006
Serotonin Depletion Attenuates AY‐9944–Mediated Atypical Absence Seizures
Summary:  Purpose: To test the hypothesis that serotonin (5‐HT) plays a role in the modulation of experimental atypical absence… 
Highly Cited
2004
Highly Cited
2004
Formation of 7-dehydrocholesterol-containing membrane rafts in vitro and in vivo, with relevance to the Smith-Lemli-Opitz syndrome Published, JLR Papers in Press, November 1, 2003. DOI 10.1194/jlr…
Smith-Lemli-Opitz syndrome (SLOS) is a recessive disease typified by 7-dehydrocholesterol (7DHC) accumulation and depletion of… 
2000
2000
Effect of inhibition of sterol delta 14-reductase on accumulation of meiosis-activating sterol and meiotic resumption in cumulus-enclosed mouse oocytes in vitro.
Two sterols of the cholesterol biosynthetic pathway induce resumption of meiosis in mouse oocytes in vitro. The sterols, termed… 
Review
1998
Review
1998
Disorders of cholesterol biosynthesis
Only four of over 30 possible defects of cholesterol biosynthesis have been described. Mevalonic aciduria due to mevalonate… 
1995
1995
Cholesterol biosynthesis from lanosterol: regulation and purification of rat hepatic sterol 14-reductase.
Review
1992
Review
1992
Pharmacological models of generalized absence seizures in rodents.
Highly Cited
1990
Highly Cited
1990
Paradoxical role of GABA in a chronic model of petit mal (absence)-like epilepsy in the rat.
1988
1988
Cholesterol prevents the teratogenic action of AY 9944: importance of the timing of cholesterol supplementation to rats.
These studies were conducted to determine whether dietary cholesterol supplementation could prevent fetal malformations induced… 
Highly Cited
1980
Highly Cited
1980
Teratogenic effect of an inhibitor of cholesterol synthesis (AY 9944) in rats: correlation with maternal cholesterolemia.
The teratogenic action of AY 9944, an inhibitor of cholesterol synthesis, was previously shown. Its prevention by simultaneous… 
1975
1975
Changes in brain hydrolytic enzyme activities in rats treated with cholesterol biosynthesis inhibitor, AY9944
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