ATP-Dependent Phosphoenolpyruvate Carboxykinase

Known as: ATP Dependent Phosphoenolpyruvate Carboxykinase, Phosphoenolpyruvate Carboxykinase, ATP-Dependent, ATP:oxaloacetate carboxy-lyase (transphosphorylating) 
An enzyme of the lyase class that catalyzes the conversion of ATP and oxaloacetate to ADP, phosphoenolpyruvate, and carbon dioxide. The enzyme is… (More)
National Institutes of Health

Papers overview

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2009
2009
Pancreatic beta-cells couple the oxidation of glucose to the secretion of insulin. Apart from the canonical K(ATP)-dependent… (More)
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Highly Cited
2009
Highly Cited
2009
OBJECTIVE The hepatic integration of human adipose tissue derived mesenchymal stem cells (hAT-MSCs) in vivo with or without prior… (More)
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Highly Cited
2007
Highly Cited
2007
When dietary carbohydrate is unavailable, glucose required to support metabolism in vital tissues is generated via… (More)
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Highly Cited
2007
Highly Cited
2007
AIMS At present, clinical success of hepatocyte transplantation as an alternative to whole liver transplantation is hampered by… (More)
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Highly Cited
2006
Highly Cited
2006
Inactivation of the von Hippel-Lindau tumor suppressor, pVHL, is associated with both hereditary and sporadic renal cysts and… (More)
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2005
Highly Cited
2005
The mechanism by which increased central adiposity causes hepatic insulin resistance is unclear. The "portal hypothesis… (More)
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Highly Cited
2004
Highly Cited
2004
Liver-specific phosphoenolpyruvate carboxykinase (PEPCK) null mice, when fasted, maintain normal whole body glucose kinetics but… (More)
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Highly Cited
1998
Highly Cited
1998
Low birth weight in humans is predictive of insulin resistance and diabetes in adult life. The molecular mechanisms underlying… (More)
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Highly Cited
1997
Highly Cited
1997
Several candidate genes for non-insulin-dependent diabetes mellitus (NIDDM) map on chromosome 20, including the… (More)
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Highly Cited
1994
Highly Cited
1994
An increase in hepatic gluconeogenesis is believed to be an important factor responsible for the fasting hyperglycemia detected… (More)
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