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ASI-222

Known as: (3 beta,5 beta)-3-((4-amino-4,6-dideoxy-beta-D-galactopyranosyl)oxy)-14-hydroxycard-20(22)-enolide, ASI 222 
 
National Institutes of Health

Papers overview

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1989
1989
We compared the abilities of digoxin and aminogalactose digitoxigenin (ASI-222) to bind to, or inhibit, purified dog heart Na+,K… Expand
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1985
1985
The effect of therapeutic doses of digitalis in modifying neural activity has been the subject of considerable controversy. In… Expand
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1984
1984
The narrow therapeutic range of cardiac glycosides continually challenges chemists to synthetize new derivatives with improved… Expand
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1983
1983
We studied the metabolism and cardiac actions of a polar aminocardenolide, 3-beta-O-(4-amino-4,6-dideoxy-beta-D-galactopyranosyl… Expand
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1982
1982
Digoxin acts at central neural (CNS) as well as peripheral sites after intravenous administration. In contrast, the analog, 3… Expand
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1981
1981
Neural activation by digitalis has been shown to facilitate the development of cardiac arrhythmias and to mediate digitalis… Expand
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1978
1978
It has been suggested that central nervous system (CNS) neuroexcitation plays an important role in digitalis-induced cardiac… Expand
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1978
1978
Two aminosugar cardiac glycosides, 3-beta-O-(4-amino-4,6-dideoxy-beta-D-galactopyranosyl) digitoxigenin (ASI-222) and its 4… Expand
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1977
1977
The effects of ASI-222 HCl and digoxin on cardiac contractile force, dP/dt, heart rate and mean blood pressure in the dog were… Expand
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1976
1976
ASI-222,3beta-O-(4-amino-4,6-dideoxy-beta-d-galactopyranosyl) digitoxigenin, is a semi-synthetic cardiac glycoside patterned… Expand
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