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ASI-222

Known as: (3 beta,5 beta)-3-((4-amino-4,6-dideoxy-beta-D-galactopyranosyl)oxy)-14-hydroxycard-20(22)-enolide, ASI 222 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Digitoxigenin
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1989
1989
Comparative ability of digoxin and an aminosugar cardiac glycoside to bind to and inhibit Na+,K+-adenosine triphosphatase. Effect of potassium.
1985
1985
Digitoxin therapy partially restores cardiac catecholamine and brain serotonin metabolism in congestive heart failure.
1983
1983
Metabolism and cardiac actions of a polar aminocardenolide and digoxin in the conscious dog.
We studied the metabolism and cardiac actions of a polar aminocardenolide, 3-beta-O-(4-amino-4,6-dideoxy-beta-D-galactopyranosyl… 
1982
1982
Effect of Digoxin and Amino Sugar Cardiac Glycoside (ASI‐222) on Plasma Antidiuretic Hormone Activity
Summary Digoxin acts at central neural (CNS) as well as peripheral sites after intravenous administration. In contrast, the… 
1982
1982
Adrenergic and cholinergic mechanisms in digitalis inotropy.
In anesthetized dogs, the effects of peripheral cardiac nerves upon cardiotonic steroid-induced contractile force increases were… 
1981
1981
Localization of the Neurally Mediated Coronary Vasoconstrictor Properties of Digitalis in the Cat
Neural activation by digitalis has been shown to facilitate the development of cardiac arrhythmias and to mediate digitalis… 
1979
1979
Structure‐Activity Relationships of an Aminosugar Cardiac Glycoside, ASI‐222 HCl, in the Heart‐Lung Preparation of the Dog
Synopsis: ASI-222 [3-β-O-(4-amino-4, 6-dideoxy-β-D-galactopyranosyl) digitoxigenin HCl] is a semisynthetic aminosugar cardiac… 
1978
1978
Inotropic and Toxic Effects of a Polar Cardiac Glycoside Derivative in the Dog
It has been suggested that central nervous system (CNS) neuroexcitation plays an important role in digitalis-induced cardiac… 
1978
1978
Comparison of the effects of aminosugar cardiac glycosides with ouabain and digoxin on Na+, K+ -adenosine triphosphatase and cardiac contractile force.
Two aminosugar cardiac glycosides, 3-beta-O-(4-amino-4,6-dideoxy-beta-D-galactopyranosyl) digitoxigenin (ASI-222) and its 4… 
1976
1976
Pharmacological studies of a new 4-aminosugar cardiac glycoside (ASI-222).
ASI-222,3beta-O-(4-amino-4,6-dideoxy-beta-d-galactopyranosyl) digitoxigenin, is a semi-synthetic cardiac glycoside patterned… 
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