ARHGEF12 gene

Known as: ARHGEF12, KIAA0382, Rho Guanine Nucleotide Exchange Factor (GEF) 12 Gene 
This gene plays a role in both G-protein coupled receptor- and Rho-mediated signaling.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2018
024619992018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Primary open-angle glaucoma (POAG) is a blinding disease. Two important risk factors for this disease are a positive family… (More)
  • table 1
  • figure 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
2010
2010
OBJECTIVE The goals of this study were to identify the signaling pathway by which sphingosine 1-phosphate (S1P) activates RhoA in… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2009
2009
Neuronal axons are guided by attractive and repulsive cues in their local environment. Because the repulsive guidance molecule A… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2004
2004
PDZ-RhoGEF, LARG, and p115RhoGEF are members of a newly identified family of Rho-guanine nucleotide exchange factors (GEFs… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
The small GTPase RhoA is involved in the regulation of various cellular functions like the remodeling of the actin cytoskeleton… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Heterotrimeric G proteins, G12 and G13, have been shown to transduce signals from G protein-coupled receptors to activate Rho… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2002
2002
The Rho family GTPase has been implicated in plexin-B1, a receptor for Semaphorin 4D (Sema4D), mediating signal transduction. Rho… (More)
Is this relevant?
2002
2002
Small GTPases of the Rho-family, like Rho, Rac and Cdc42, are involved in neuronal morphogenesis by regulating growth cone… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
A putative guanine nucleotide exchange factor (GEF), termed leukemia-associated RhoGEF (LARG), was recently identified upon… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
We have identified a gene at 11q23, telomeric to MLL, that encodes a guanine nucleotide exchange factor (GEF). This gene is… (More)
Is this relevant?