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ARHGEF12 gene

Known as: ARHGEF12, KIAA0382, RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 12 
This gene plays a role in both G-protein coupled receptor- and Rho-mediated signaling.
National Institutes of Health

Papers overview

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2015
2015
Primary open-angle glaucoma (POAG) is a blinding disease. Two important risk factors for this disease are a positive family… Expand
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Highly Cited
2011
Highly Cited
2011
How individual cells respond to mechanical forces is of considerable interest to biologists as force affects many aspects of cell… Expand
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Highly Cited
2007
Highly Cited
2007
Adhesion of cells to extracellular matrix proteins such as fibronectin initiates signaling cascades that affect cell morphology… Expand
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Highly Cited
2006
Highly Cited
2006
In this study we have examined the interaction of CD44 (a major hyaluronan (HA) receptor) with a RhoA-specific guanine nucleotide… Expand
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Highly Cited
2006
Highly Cited
2006
The strict spatio-temporal control of Rho GTPases is critical for many cellular functions, including cell motility, contractility… Expand
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Highly Cited
2004
Highly Cited
2004
PDZ-RhoGEF, LARG, and p115RhoGEF are members of a newly identified family of Rho-guanine nucleotide exchange factors (GEFs… Expand
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Highly Cited
2003
Highly Cited
2003
The small GTPase RhoA is involved in the regulation of various cellular functions like the remodeling of the actin cytoskeleton… Expand
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Highly Cited
2002
Highly Cited
2002
Semaphorins are axon guidance molecules that signal through the plexin family of receptors. Semaphorins also play a role in other… Expand
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Highly Cited
2002
Highly Cited
2002
A recently identified family of guanine nucleotide exchange factors for Rho that includes PDZ-RhoGEF, LARG, and p115RhoGEF… Expand
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Highly Cited
2002
Highly Cited
2002
The Rho family GTPase has been implicated in plexin-B1, a receptor for Semaphorin 4D (Sema4D), mediating signal transduction. Rho… Expand
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