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ARHGAP1 gene

Known as: RHOGAP1, p50rhoGAP, GTPase-ACTIVATING PROTEIN, RHO, 1 
National Institutes of Health

Papers overview

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Highly Cited
2018
Highly Cited
2018
Significance Prostate cancer is one of most common cancers in men worldwide, and osteoblastic bone metastasis is frequently… Expand
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Highly Cited
2009
Highly Cited
2009
Bone mineral density (BMD) is a heritable complex trait used in the clinical diagnosis of osteoporosis and the assessment of… Expand
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Highly Cited
2008
Highly Cited
2008
PURPOSE Early/initiating oncogenic mutations have been identified for many cancers, but such mutations remain unidentified in… Expand
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Highly Cited
2006
Highly Cited
2006
Regulation by Rho-type small GTPases, such as RAC5, is important for the maintenance of polarity in tobacco (Nicotiana tabacum… Expand
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Highly Cited
2000
Highly Cited
2000
Rho GTPases direct actin rearrangements in response to a variety of extracellular signals. P190 RhoGAP (GTPase activating protein… Expand
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Highly Cited
1999
Highly Cited
1999
rna1p is the Schizosaccharomyces pombe ortholog of the mammalian GTPase-activating protein (GAP) of Ran. Both proteins are… Expand
Highly Cited
1998
Highly Cited
1998
The isolation of genes involved in cancer development is critical for uncovering the molecular basis of cancer. We report here… Expand
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Highly Cited
1997
Highly Cited
1997
Small G proteins of the Rho family, which includes Rho, Rac and Cdc42Hs, regulate phosphorylation pathways that control a range… Expand
Highly Cited
1997
Highly Cited
1997
Small G proteins transduce signals from plasma-membrane receptors to control a wide range of cellular functions,. These proteins… Expand
Highly Cited
1996
Highly Cited
1996
We previously described IQGAP1 as a human protein related to a putative Ras GTPase-activating protein (RasGAP) from the fission… Expand