ARHGAP1 gene

Known as: RHOGAP1, p50rhoGAP, GTPase-ACTIVATING PROTEIN, RHO, 1 
 
National Institutes of Health

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2 relations
ARHGAP26 generho GTPase-activating protein

Papers overview

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Highly Cited
2009
Highly Cited
2009
Twenty bone mineral density loci identified by large-scale meta-analysis of genome-wide association studies
Bone mineral density (BMD) is a heritable complex trait used in the clinical diagnosis of osteoporosis and the assessment of… (More)
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2008
2008
p190A RhoGAP is a glycogen synthase kinase-3-beta substrate required for polarized cell migration.
The Rho GTPases are critical regulators of the actin cytoskeleton and are required for cell adhesion, migration, and polarity… (More)
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Highly Cited
2007
Highly Cited
2007
Oncogenic inhibition by a deleted in liver cancer gene requires cooperation between tensin binding and Rho-specific GTPase-activating protein activities.
The three deleted in liver cancer genes (DLC1-3) encode Rho-GTPase-activating proteins (RhoGAPs) whose expression is frequently… (More)
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Highly Cited
2006
Highly Cited
2006
Tobacco RhoGTPase ACTIVATING PROTEIN1 spatially restricts signaling of RAC/Rop to the apex of pollen tubes.
Regulation by Rho-type small GTPases, such as RAC5, is important for the maintenance of polarity in tobacco (Nicotiana tabacum… (More)
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2005
2005
p190 Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling.
Plexins are transmembrane receptors for semaphorins, guiding cell migration and axon extension. Plexin activation leads to the… (More)
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2002
2002
Fear Memory Formation Involves p190 RhoGAP and ROCK Proteins through a GRB2-Mediated Complex
We used fear conditioning, which is known to alter synaptic efficacy in lateral amygdala (LA), to study molecular mechanisms… (More)
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Highly Cited
2000
Highly Cited
2000
The adhesion signaling molecule p190 RhoGAP is required for morphogenetic processes in neural development.
Rho GTPases direct actin rearrangements in response to a variety of extracellular signals. P190 RhoGAP (GTPase activating protein… (More)
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1999
1999
Inhibition of RhoGAP activity is sufficient for the induction of Rho-mediated actin reorganization.
It is generally believed that the induction of actin cytoskeleton rearrangements by extracellular stimuli results from the… (More)
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Highly Cited
1998
Highly Cited
1998
Cloning, characterization, and chromosomal localization of a gene frequently deleted in human liver cancer (DLC-1) homologous to rat RhoGAP.
The isolation of genes involved in cancer development is critical for uncovering the molecular basis of cancer. We report here… (More)
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Highly Cited
1996
Highly Cited
1996
The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases.
We previously described IQGAP1 as a human protein related to a putative Ras GTPase-activating protein (RasGAP) from the fission… (More)
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