ARGININOSUCCINATE SYNTHASE

Known as: Synthetase, Argininosuccinate, Argininosuccinate Synthase [Chemical/Ingredient], L-Citrulline:L-aspartate ligase (AMP-forming) 
An enzyme of the urea cycle that catalyzes the formation of argininosuccinic acid from citrulline and aspartic acid in the presence of ATP. Absence… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
The levels of L-arginine, a cationic, semi-essential amino acid, are often controlled within a cell at the level of local… (More)
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Highly Cited
2009
Highly Cited
2009
Arginine deprivation as an anticancer therapy has historically been met with limited success. The development of pegylated… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE Malignant pleural mesothelioma (MPM) is an increasing health burden on many societies worldwide and, being generally… (More)
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Review
2005
Review
2005
Citrulline (Cit, C6H13N3O3), which is a ubiquitous amino acid in mammals, is strongly related to arginine. Citrulline metabolism… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Argininosuccinate synthetase (ASS) was the first of two enzymes to convert citrulline to arginine. This pathway… (More)
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2004
2004
Although cellular levels of arginine greatly exceed the apparent K(m) for endothelial nitric-oxide synthase, current evidence… (More)
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Review
2003
Review
2003
Argininosuccinate synthetase (ASS, EC 6.3.4.5) catalyses the condensation of citrulline and aspartate to form argininosuccinate… (More)
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Review
1996
Review
1996
The radical nitric oxide (NO) is a possible mediator of pancreatic beta-cell damage in insulin-dependent diabetes mellitus (IDDM… (More)
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1996
1996
Nitric oxide (NO) is synthesized from arginine by nitric oxide synthase (NOS), and citrulline which is generated can be recycled… (More)
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Highly Cited
1992
Highly Cited
1992
Genetic studies have implicated the early involvement of a gene on chromosome arm 9p in the development of cutaneous melanoma. We… (More)
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