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APLF gene

Known as: CHROMOSOME 2 OPEN READING FRAME 13, APLF, APRATAXIN- AND PNK-LIKE FACTOR 
 
National Institutes of Health

Papers overview

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Review
2014
Review
2014
Artemis and PALF (also called APLF) appear to be among the primary nucleases involved in non-homologous end joining (NHEJ) and… Expand
2013
2013
APLF is a forkhead associated-containing protein with poly(ADP-ribose)-binding zinc finger (PBZ) domains, which undergoes… Expand
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Highly Cited
2011
Highly Cited
2011
PARP-3 is a member of the ADP-ribosyl transferase superfamily of unknown function. We show that PARP-3 is stimulated by DNA… Expand
Highly Cited
2011
Highly Cited
2011
Poly(ADP-ribosyl)ation plays a major role in DNA repair, where it regulates chromatin relaxation as one of the critical events in… Expand
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Highly Cited
2009
Highly Cited
2009
Short-patch repair of DNA single-strand breaks and gaps (SSB) is coordinated by XRCC1, a scaffold protein that recruits the DNA… Expand
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Highly Cited
2008
Highly Cited
2008
ABSTRACT APLF is a novel protein of unknown function that accumulates at sites of chromosomal DNA strand breakage via forkhead… Expand
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Highly Cited
2008
Highly Cited
2008
Nonhomologous end-joining (NHEJ) is the major mammalian DNA double-strand break (DSB) repair pathway of DSBs induced by DNA… Expand
Highly Cited
2007
Highly Cited
2007
ABSTRACT Aprataxin and polynucleotide kinase (PNK) are DNA end processing factors that are recruited into the DNA single- and… Expand
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Highly Cited
2007
Highly Cited
2007
DNA strand breaks arise continuously as the result of intracellular metabolism and in response to a multitude of genotoxic agents… Expand
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Highly Cited
1993
Highly Cited
1993
Twelve x-ray-induced transcripts (xips), differentially expressed 8- to 230-fold in x-irradiated versus unirradiated… Expand