APEX1 gene

Known as: APURINIC/APYRIMIDINIC EXONUCLEASE, HUMAN APURINIC ENDONUCLEASE 1, REDOX FACTOR 1 
This gene is involved in DNA repair processes.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1971-2018
010203019712018

Papers overview

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2011
2011
PURPOSE To explore whether functional single nucleotide polymorphisms (SNPs) of base-excision repair genes are predictors of… (More)
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2010
Highly Cited
2010
Apurinic/apyrimidinic endonuclease-1 (APE1) is an essential enzyme in the base excision repair (BER) pathway. Here, we show that… (More)
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2009
2009
Apurinic/apyrimidinic endonuclease 1 (APE1) is an essential enzyme in the base excision repair pathway, which is the primary… (More)
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2008
2008
BACKGROUND Genetic polymorphisms of DNA repair enzymes may lead to genetic instability and colorectal cancer carcinogenesis. Our… (More)
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Highly Cited
2008
Highly Cited
2008
Colorectal cancer represents a complex disease where susceptibility may be influenced by genetic polymorphisms in the DNA repair… (More)
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2007
Highly Cited
2007
To mitigate the oxidative damage inflicted by biotic or abiotic stresses, plants have evolved complex anti-oxidative defense… (More)
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2005
Highly Cited
2005
PURPOSE Several DNA repair gene polymorphisms have been described, which affect DNA repair capacity and modulate cancer… (More)
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2005
2005
The base excision repair (BER) pathway is essential for the removal of DNA bases damaged by alkylation or oxidation. A key step… (More)
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2002
Highly Cited
2002
The plant genome is a highly redundant and dynamic genome. Here, we show that double antisense plants lacking the two major… (More)
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2001
Highly Cited
2001
Although several variants of DNA repair genes have been identified, their functional significance has not been determined. Using… (More)
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