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AN 215

Known as: AN-215 
 
National Institutes of Health

Papers overview

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2010
2010
Bombesin (BN) and gastrin‐releasing peptide (GRP) have been shown to stimulate the growth of human prostate cancer in vivo and in… Expand
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2006
2006
We developed a powerful cytotoxic analogue of bombesin AN‐215, in which the bombesin (BN)‐like carrier peptide is conjugated to 2… Expand
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2006
2006
The aim of this study was to investigate the effect of treatment of experimental ovarian cancers with targeted cytotoxic analogs… Expand
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2005
2005
The cytotoxic analog of bombesin (BN)/gastrin releasing peptide (GRP) AN-215 consisting of 2-pyrrolinodoxorubicin (AN-201), a… Expand
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Review
2005
Review
2005
Chemotherapy is one of the main modalities in the therapy of cancer. However, an improvement in the efficacy and a reduction in… Expand
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2005
2005
Multidrug resistance (MDR) mediated by membrane transporters, such as P‐glycoprotein (MDR‐1) and MDR‐associated protein (MRP… Expand
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2002
2002
Some brain tumours, such as glioblastomas express high levels of receptors for bombesin/gastrin releasing peptide. We… Expand
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Highly Cited
2000
Highly Cited
2000
The effectiveness of chemotherapy targeted to bombesin (BN) receptors was evaluated in nude mice bearing PC‐3 human androgen… Expand
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Review
1999
Review
1999
In view of non-specific toxicity of most chemotherapeutic agents against normal cells, the development of targeted chemotherapy… Expand
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1999
1999
SummaryRecently, we developed a powerful cytotoxic analogue of bombesin AN-215, in which the bombesin-like carrier peptide Gln… Expand
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