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AN 215

Known as: AN-215 
National Institutes of Health

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3 relations

Broader (2)

BombesinDoxorubicin
analogs & derivatives

Papers overview

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2008
2008
Therapy of experimental hepatic cancers with cytotoxic peptide analogs targeted to receptors for luteinizing hormone-releasing hormone, somatostatin or bombesin
As there is no effective systemic therapy for advanced hepatocellular carcinoma (HCC), we investigated the presence of receptors… 
2006
2006
Targeted chemotherapy with cytotoxic bombesin analogue AN‐215 inhibits growth of experimental human prostate cancers
We developed a powerful cytotoxic analogue of bombesin AN‐215, in which the bombesin (BN)‐like carrier peptide is conjugated to 2… 
2005
2005
Effective Inhibition of Experimental Human Ovarian Cancers with a Targeted Cytotoxic Bombesin Analogue AN-215
Purpose: To determine whether the cytotoxic analogue of bombesin/gastrin-releasing peptide (GRP) AN-215 can inhibit the in vivo… 
2005
2005
Targeted chemotherapy with cytotoxic bombesin analogue AN‐215 can overcome chemoresistance in experimental renal cell carcinomas
Multidrug resistance (MDR) mediated by membrane transporters, such as P‐glycoprotein (MDR‐1) and MDR‐associated protein (MRP… 
2005
2005
Inhibition of Growth of Experimental Human and Hamster Pancreatic Cancers In Vivo by a Targeted Cytotoxic Bombesin Analog
Objectives: Targeting anticancer agents to receptors for peptide hormones such as bombesin/gastrin-releasing peptide (GRP) on… 
2005
2005
Experimental therapy of human endometrial cancers with a targeted cytotoxic bombesin analog AN-215: low induction of multidrug resistance proteins.
2003
2003
Preclinical evaluation of therapeutic effects of targeted cytotoxic analogs of somatostatin and bombesin on human gastric carcinomas
New modalities are necessary for the treatment of patients with unresectable gastric carcinoma. The authors investigated whether… 
2002
2002
Effective treatment of experimental U-87MG human glioblastoma in nude mice with a targeted cytotoxic bombesin analogue, AN-215
Some brain tumours, such as glioblastomas express high levels of receptors for bombesin/gastrin releasing peptide. We… 
2002
2002
AN-215 successfully inhibits glioblastoma tumour growth in a murine model
  • 2002
  • Corpus ID: 195151116
1999
1999
Targeting of cytotoxic bombesin analog AN-215 to H-69 small cell lung carcinoma as demonstrated by semi-quantitative microsatellite analysis in vitro
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