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AMG 162

Known as: 162, AMG, AMG-162 
 
National Institutes of Health

Papers overview

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Review
2011
Review
2011
Introduction: Denosumab, a fully human monoclonal antibody, targets the receptor activator of nuclear factor-kappaB (RANK) ligand… Expand
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Review
2009
Review
2009
Objective: To review the pharmacology, pharmacokinetics, pharmacodynamics, safety, efficacy, and use of denosumab in osteoporosis… Expand
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2008
2008
Denosumab (AMG 162) is an investigational fully human monoclonal antibody with a high affinity and specificity for receptor… Expand
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Review
2006
Review
2006
PURPOSE OF REVIEW Inflammation-induced osteolysis is a problem in both inflammatory arthritis and total joint arthroplasty. New… Expand
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Review
2005
Review
2005
Bone health is an increasingly important concern in breast cancer survivors because in postmenopausal women, bone-sparing… Expand
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2005
2005
Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the… Expand
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2005
2005
Oncologists have always been dedicated to fully understanding the toxicities associated with the cancer treatments they… Expand
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Review
2005
Review
2005
RANKL is an essential factor for osteoclastogenesis. Amgen research group has developed AMG 162, a fully human monoclonal… Expand
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Highly Cited
2004
Highly Cited
2004
UNLABELLED The safety and bone antiresorptive effect of a single subcutaneous dose of AMG 162, a human monoclonal antibody to… Expand
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2004
2004
8106 Background: RANKL is an essential osteoclastic differentiation/activation factor. AMG 162 PK and PD were evaluated in a… Expand
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