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ALX-0081
Known as:
ALX 0081
, ALX0681
, ALX0081
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National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
caplacizumab
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Balancing Scattering Channels: A Panoscopic Approach toward Zero Temperature Coefficient of Resistance Using High‐Entropy Alloys
S. Shafeie
,
S. Guo
,
P. Erhart
,
Q. Hu
,
A. Palmqvist
Advanced materials
2019
Corpus ID: 53213634
Designing alloys with an accurate temperature‐independent electrical response over a wide temperature range, specifically a low…
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2017
2017
Composite Electrolyte for All-Solid-State Lithium Batteries: Low-Temperature Fabrication and Conductivity Enhancement.
Sang-Don Lee
,
Kyu-Nam Jung
,
+4 authors
Jong‐Won Lee
ChemSusChem
2017
Corpus ID: 21096016
All-solid-state lithium batteries offer notable advantages over conventional Li-ion batteries with liquid electrolytes in terms…
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Review
2013
Review
2013
Novel Antiplatelet Agents: ALX-0081, a Nanobody Directed towards von Willebrand Factor
J. Bartunek
,
E. Barbato
,
G. Heyndrickx
,
M. Vanderheyden
,
W. Wijns
,
J. Holz
Journal of Cardiovascular Translational Research
2013
Corpus ID: 5560641
This manuscript reviews the studies performed with ALX-0081 (INN: caplacizumab), a Nanobody targeting von Willebrand factor, in…
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Highly Cited
2013
Highly Cited
2013
Reperfusion of cerebral artery thrombosis by the GPIb-VWF blockade with the Nanobody ALX-0081 reduces brain infarct size in guinea pigs.
S. Momi
,
M. Tantucci
,
M. van Roy
,
H. Ulrichts
,
Giovanni Ricci
,
P. Gresele
Blood
2013
Corpus ID: 206916520
Thrombolytic therapy is the cornerstone of treatment of acute atherothrombotic ischemic stroke but is associated with brain…
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Highly Cited
2012
Highly Cited
2012
Evaluation of efficacy and safety of the anti-VWF Nanobody ALX-0681 in a preclinical baboon model of acquired thrombotic thrombocytopenic purpura.
F. Callewaert
,
J. Roodt
,
+7 authors
J. Holz
Blood
2012
Corpus ID: 10228896
ALX-0681 is a therapeutic Nanobody targeting the A1-domain of VWF. It inhibits the interaction between ultra-large VWF and…
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Highly Cited
2011
Highly Cited
2011
Antithrombotic drug candidate ALX-0081 shows superior preclinical efficacy and safety compared with currently marketed antiplatelet drugs.
H. Ulrichts
,
K. Silence
,
+11 authors
J. Holz
Blood
2011
Corpus ID: 16192562
Neutralizing the interaction of the platelet receptor gpIb with VWF is an attractive strategy to treat and prevent thrombotic…
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2011
2011
The in vitro effect of the new antithrombotic drug candidate ALX-0081 on blood samples of patients undergoing percutaneous coronary intervention.
J. V. van Loon
,
P. D. De Jaegere
,
+5 authors
F. Leebeek
Thrombosis and haemostasis
2011
Corpus ID: 36881338
Compound ALX-0081 is a bivalent humanised Nanobody® that binds the A1-domain of von Willebrand factor (VWF) with high affinity…
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Review
2010
Review
2010
Targeting von Willebrand factor and platelet glycoprotein Ib receptor
C. Firbas
,
J. Siller-Matula
,
B. Jilma
Expert review of cardiovascular therapy
2010
Corpus ID: 11253976
Atherothrombotic events, such as acute coronary syndrome or stroke, are the result of platelet activation. Von Willebrand factor…
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2009
2009
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Anti-Vwf Nanobody® ALX-0681 After Single and Multiple Subcutaneous Administrations to Healthy Volunteers.
Khalid Abd-Elaziz
,
P. Kamphuisen
,
+9 authors
J. Holz
2009
Corpus ID: 208429873
ALX-0681 is a humanized bivalent Nanobody®, that binds to the A1 domain of von Willebrand factor (vWF) and hence blocks its…
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2002
2002
Positron Lifetime Study of Defect Structures in B2 Ordered Co-Al Alloys
H. Araki
,
T. Mimura
,
P. Chalermkarnnon
,
M. Mizuno
,
Y. Shirai
2002
Corpus ID: 54846514
The positron lifetimes in the B2 intermetallic compounds Co100−XAlX (X=46.9 to 54.1) water-quenched, air- and furnace-cooled from…
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