AG7088

Known as: AG 7088, AG-7088 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2016
02419992016

Papers overview

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2013
2013
Enterovirus-71 (EV71) infections can cause life-threatening diseases with neurological symptoms. Currently, no direct targeting… (More)
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2008
2008
Human enterovirus (EV) belongs to the picornavirus family, which consists of over 200 medically relevant viruses. A… (More)
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2007
2007
Coxsackievirus B3 (CVB3) 3C protease (3CP) plays essential roles in the viral replication cycle, and therefore, provides an… (More)
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2005
2005
The picornavirus 3C protease is required for the majority of proteolytic cleavages that occur during the viral life cycle… (More)
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2004
2004
Pharmacophore modeling can provide valuable insight into ligand-receptor interactions. It can also be used in 3D (dimensional… (More)
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2000
2000
BACKGROUND We tested the in vitro activity of pleconaril and AG7088 against five numbered human rhinovirus (HRV) serotypes and 46… (More)
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2000
2000
Symptom severity in patients with human rhinovirus (HRV)-induced respiratory illness is associated with elevated levels of the… (More)
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1999
1999
AG7088 is a potent, irreversible inhibitor of human rhinovirus (HRV) 3C protease (inactivation rate constant (k(obs)/[I]) = 1,470… (More)
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Highly Cited
1999
Highly Cited
1999
Human rhinoviruses, the most important etiologic agents of the common cold, are messenger-active single-stranded monocistronic… (More)
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1999
1999
The structure-based design, chemical synthesis, and biological evaluation of various human rhinovirus (HRV) 3C protease (3CP… (More)
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