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AG-879

Known as: AG 879, AG879, Tyrphostin AG 879 
A compound that selectively inhibits protein tyrosine kinase and nerve growth factor-dependent tyrosine phosphorylation. (NCI)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Decorin, a member of the small leucine-rich proteoglycan gene family, down-regulates members of the ErbB receptor tyrosine kinase… Expand
Highly Cited
2006
Highly Cited
2006
Coexpression of the epidermal growth factor receptor (EGFR) family receptors is found in a subset of colon cancers, which may… Expand
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Highly Cited
2006
Highly Cited
2006
Background: The neurotrophin nerve growth factor (NGF) has been implicated as a mediator in allergic asthma. Direct evidence that… Expand
Highly Cited
2005
Highly Cited
2005
The involvement of protein tyrosine kinases (PTKs) in aryl hydrocarbon receptor (AhR)-mediated signalling by omeprazole and 2,3,7… Expand
Highly Cited
2003
Highly Cited
2003
We have found that neuregulin-1beta (NRG-1beta) is expressed in the cardiac microvascular endothelium, and promotes the growth… Expand
Highly Cited
2003
Highly Cited
2003
The expression and secretion of prostate-specific antigen (PSA) are regulated by androgens in normal prostate secretory… Expand
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Highly Cited
2002
Highly Cited
2002
We investigated the ability of GM1 to induce phosphorylation of the tyrosine kinase receptor for neurotrophins, Trk, in rat brain… Expand
Highly Cited
2001
Highly Cited
2001
Interleukin-6 (IL-6) induces prostate cancer (CaP) cell proliferation in vitro. Several lines of evidence suggest that IL-6 may… Expand
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Highly Cited
1999
Highly Cited
1999
Overexpression of the HER2/Neu protooncogene has been linked to the progression of breast cancer. Here we demonstrate that the… Expand
Highly Cited
1993
Highly Cited
1993
A series of the synthetic protein kinase inhibitors known as tyrphostins were examined for their effects on the tyrosine… Expand