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Decorin, a member of the small leucine-rich proteoglycan gene family, down-regulates members of the ErbB receptor tyrosine kinase… Expand Coexpression of the epidermal growth factor receptor (EGFR) family receptors is found in a subset of colon cancers, which may… Expand Background: The neurotrophin nerve growth factor (NGF) has been implicated as a mediator in allergic asthma. Direct evidence that… Expand The involvement of protein tyrosine kinases (PTKs) in aryl hydrocarbon receptor (AhR)-mediated signalling by omeprazole and 2,3,7… Expand We have found that neuregulin-1beta (NRG-1beta) is expressed in the cardiac microvascular endothelium, and promotes the growth… Expand The expression and secretion of prostate-specific antigen (PSA) are regulated by androgens in normal prostate secretory… Expand We investigated the ability of GM1 to induce phosphorylation of the tyrosine kinase receptor for neurotrophins, Trk, in rat brain… Expand Interleukin-6 (IL-6) induces prostate cancer (CaP) cell proliferation in vitro. Several lines of evidence suggest that IL-6 may… Expand Overexpression of the HER2/Neu protooncogene has been linked to the progression of breast cancer. Here we demonstrate that the… Expand A series of the synthetic protein kinase inhibitors known as tyrphostins were examined for their effects on the tyrosine… Expand