FAQ

ADRBK2 gene

Known as: adrenergic, beta, receptor kinase 2, GRK3, BARK2 
This gene plays a role in signal transduction.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2012
01219962012

Related topics

Related topics

6 relations
ADRBK1 geneBeta-Adrenergic Receptor Kinase 2G Protein-Coupled Receptor SignalingPhosphorylation
(More)

Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
ADRBK2 gene
Signal Transduction
Phosphorylation
Beta-Adrenergic Receptor Kinase 2
G Protein-Coupled Receptor Signaling
ADRBK1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Activity of β2-adrenergic receptor in oral squamous cell carcinoma is mediated by overexpression of the ADRBK2 gene: a pilot study.
The β2-adrenergic receptor is most frequently involved in carcinogenic processes. Earlier studies have established a relation… (More)
  • table 1
  • table 2
  • figure 1
  • table 3
  • figure 2
Is this relevant?
2010
2010
Allele specific analysis of the ADRBK2 gene in lymphoblastoid cells from bipolar disorder patients.
G-protein coupled receptor kinase-3 (GRK3), translated from the gene, ADRBK2 has been implicated as a candidate molecule for… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 4
  • figure 3
Is this relevant?
2007
2007
Role of 90-kDa heat shock protein (Hsp 90) and protein degradation in regulating neuronal levels of G protein-coupled receptor kinase 3.
Cellular levels of G protein-coupled receptor kinase (GRK)3 determine the sensitivity of the alpha(2A/B)-adrenoceptor (alpha(2… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2007
Review
2007
Further evidence for association of GRK3 to bipolar disorder suggests a second disease mutation.
OBJECTIVES Two genome-wide linkage surveys suggest chromosome 22q12 may contain a susceptibility locus for bipolar disorder (BPD… (More)
Is this relevant?
2006
2006
Bipolar 1 disorder is not associated with the RGS4, PRODH, COMT and GRK3 genes.
Although current psychiatric nosology separates bipolar disorder and schizophrenia into non-overlapping categories, there is… (More)
Is this relevant?
2005
2005
L-DOPA reverses the MPTP-induced elevation of the arrestin2 and GRK6 expression and enhanced ERK activation in monkey brain.
Dysregulation of dopamine receptors (DARs) is believed to contribute to Parkinson disease (PD) pathology. G protein-coupled… (More)
Is this relevant?
2004
2004
Mutation screening and association study of the beta-adrenergic receptor kinase 2 gene in schizophrenia families.
Chromosome 22q12 is one of the most promising regions for harboring a risk gene for schizophrenia. We have reported significant… (More)
Is this relevant?
2002
2002
Opioid Receptor Types Selectively Cointernalize with G Protein-Coupled Receptor Kinases
Activation of G protein-coupled receptors (GPCRs) may bring about their disappearance from the cell membrane, and it is commonly… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2001
Review
2001
Distribution of G-protein-coupled receptor kinase (GRK) isoforms 2, 3, 5 and 6 mRNA in the rat brain.
There is limited knowledge about the distribution of the different G-protein-coupled receptor kinases (GRKs) in the rat brain… (More)
Is this relevant?
1996
1996
Identification by polymerase chain reaction of the G protein-coupled receptor kinases expressed in the mouse gonadotropic alpha T3-1 cell line.
G protein-coupled receptor kinases (GRK 1-6) stimulate short-term desensitization (< 5 min) by phosphorylating G-protein coupled… (More)
Is this relevant?