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ADRA2A wt Allele

Known as: ADRA2, ADRAR, Adrenoceptor, Alpha-2A Gene 
Human ADRA2A wild-type allele is located within 10q24-q26 and is approximately 4 kb in length. This allele, which encodes alpha-2A adrenergic… Expand
National Institutes of Health

Papers overview

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2008
2008
BACKGROUND:Elevated resting blood pressure (BP) and spontaneous baroreflex sensitivity (BRS) are associated with hypoalgesia to… Expand
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Highly Cited
2003
Highly Cited
2003
The basal forebrain plays an important role in the modulation of cortical activity and sleep‐wake states. Yet its role must be… Expand
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1999
1999
The 2A subtype of the alpha-adrenergic receptor (alpha2A-AR) is necessary for the hypotensive effects of clonidine and other… Expand
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1998
1998
We have investigated the potential for protein kinase C (PKC) to phosphorylate and desensitize the alpha2A-adrenergic receptor… Expand
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1998
1998
One mechanism of long-term agonist-promoted desensitization of alpha2AR function is downregulation of the cellular levels of the… Expand
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1998
1998
Truncations and chimeras of the α2A-adrenergic receptor (α2AAR) were evaluated to identify membrane domains responsible for its… Expand
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Highly Cited
1997
Highly Cited
1997
Norepinephrine contributes to antinociceptive, sedative, and sympatholytic responses in vivo, and alpha2 adrenergic receptor… Expand
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Highly Cited
1997
Highly Cited
1997
G-protein-coupled receptors demonstrate differing trafficking itineraries in polarized Madin-Darby canine kidney (MDCK II) cells… Expand
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Highly Cited
1996
Highly Cited
1996
The present studies examined the localization of the α- and α-adrenergic receptor (AR) subtypes in polarized Madin-Darby canine… Expand
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1996
1996
We have investigated potential Gi and Gs coupling domains within the intracellular regions of the alpha2AAR subtype using a… Expand
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