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ADIPOQ protein, human

Known as: apM1 adipose-specific protein, human, Gelatin-Binding Protein, apM-1 
Adiponectin (244 aa, ~26 kDa) is encoded by the human ADIPOQ gene. This protein is involved in the modulation of both glucose metabolism and lipid… 
National Institutes of Health

Related topics

Related topics

17 relations
ADIPOQ geneADIPOQ wt AlleleAdipocytesAdipocytokine Signaling Pathway

Broader (1)

Adiponectin

Papers overview

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Highly Cited
2006
Highly Cited
2006
APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function
Adiponectin, also known as Acrp30, is an adipose tissue-derived hormone with anti-atherogenic, anti-diabetic and insulin… 
Highly Cited
2004
Highly Cited
2004
Complex Distribution, Not Absolute Amount of Adiponectin, Correlates with Thiazolidinedione-mediated Improvement in Insulin Sensitivity*
Adiponectin is an adipocyte-specific secretory protein that circulates in serum as a hexamer of relatively low molecular weight… 
Highly Cited
2004
Highly Cited
2004
Insulin/Foxo1 Pathway Regulates Expression Levels of Adiponectin Receptors and Adiponectin Sensitivity*
Adiponectin/Acrp30 is a hormone secreted by adipocytes, which acts as an antidiabetic and antiatherogenic adipokine. We reported… 
Highly Cited
2003
Highly Cited
2003
Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats
Adiponectin (Acrp30) is a physiologically active polypeptide hormone secreted by adipose tissue that shows insulin-sensitizing… 
Highly Cited
2002
Highly Cited
2002
Serum adiponectin and leptin levels in patients with lipodystrophies
Lipodystrophies are characterized by selective but variable loss of body fat and metabolic complications of insulin resistance… 
Highly Cited
2002
Highly Cited
2002
Profiling gene transcription in vivo reveals adipose tissue as an immediate target of tumor necrosis factor-alpha: implications for insulin resistance.
Despite extensive studies implicating tumor necrosis factor (TNF)-alpha as a contributing cause of insulin resistance, the… 
Highly Cited
2001
Highly Cited
2001
The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
Acrp30 is a circulating protein synthesized in adipose tissue. A single injection in mice of purified recombinant Acrp30 leads to… 
Highly Cited
2001
Highly Cited
2001
Endogenous glucose production is inhibited by the adipose-derived protein Acrp30.
Intraperitoneal injection of purified recombinant Acrp30 lowers glucose levels in mice. To gain insight into the mechanism(s) of… 
Highly Cited
1996
Highly Cited
1996
Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma.
By use of its affinity to gelatin-Cellulofine, a novel protein, GBP28 (gelatin-binding protein of 28 kDa), was obtained from… 
Highly Cited
1995
Highly Cited
1995
A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes (*)
We describe a novel 30-kDa secretory protein, Acrp30 (adipocyte complement-related protein of 30 kDa), that is made exclusively… 
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