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Selection for bulls that would reach puberty early reduces the generation interval and increases fertility and herd productivity… Expand Study Design. Animal experimental study. Objective. To establish a slowly progressive and reproducible intervertebral disc… Expand Malignant melanoma is difficult to treat due to its resistance to chemotherapeutic regimens. Discovery of new pharmaceuticals… Expand Most epilepsy genes encode ion channels, but the LGI1 gene responsible for autosomal dominant partial epilepsy with auditory… Expand OBJECTIVE:To study the expression and function of the brain-specific proteinase deficient disintegrins, ADAM11 and ADAM22 (a… Expand Disintegrins are a family of potent inhibitors of cell-cell and cell-matrix adhesion. In this study we have identified a region… Expand BackgroundADAM11 is a member of the ADAM gene family and is mainly expressed in the nervous system. It is thought to be an… Expand ADAM11 is the prototype member of the predominantly CNS-associated clade of the ADAM metalloprotease-disintegrins that has been… Expand A cellular disintegrin, also called MDC and ADAM is a recently discovered gene family that encodes protein with disintegrin-like… Expand ADAMs (A disintegrin and metalloproteinase) are a recently discovered family of proteins with significant primary sequence… Expand