ADAM10 gene

Known as: ADAM metallopeptidase domain 10, A DISINTEGRIN AND METALLOPROTEINASE DOMAIN 10, AD10 
This gene plays a role in the regulation of protein cleavage.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
0204019962018

Papers overview

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Highly Cited
2010
Highly Cited
2010
The amyloid precursor protein (APP) undergoes constitutive shedding by a protease activity called alpha-secretase. This is… (More)
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2009
2009
ADAM10, a member of a disintegrin and metalloprotease family, is an alpha-secretase capable of anti-amyloidogenic proteolysis of… (More)
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Highly Cited
2006
Highly Cited
2006
CD23, the low-affinity immunoglobulin E receptor, is an important modulator of the allergic response and of diseases such as… (More)
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2006
2006
N-cadherin is essential for excitatory synaptic contact in the hippocampus. At the sites of synaptic contact, it forms a complex… (More)
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Highly Cited
2004
Highly Cited
2004
The novel CXC-chemokine ligand 16 (CXCL16) functions as transmembrane adhesion molecule on the surface of APCs and as a soluble… (More)
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Highly Cited
2003
Highly Cited
2003
The CX3C chemokine fractalkine (CX3CL1) exists as a membrane-expressed protein promoting cell-cell adhesion and as a soluble… (More)
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Highly Cited
2003
Highly Cited
2003
The putative alpha-secretase cleaves the amyloid precursor protein (APP) of Alzheimer's disease in the middle of the amyloid beta… (More)
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Highly Cited
2002
Highly Cited
2002
Communication between different signaling pathways enables cells to coordinate the responses to diverse environmental signals… (More)
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Highly Cited
1997
Highly Cited
1997
Notch and the disintegrin metalloprotease encoded by the kuzbanian (kuz) gene are both required for a lateral inhibition process… (More)
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Highly Cited
1996
Highly Cited
1996
During neurogenesis in Drosophila both neurons and nonneuronal cells are produced from a population of initially equivalent cells… (More)
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