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ACP 103

Known as: ACP-103, ACP103 
 
National Institutes of Health

Papers overview

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2011
2011
A large number of G-protein-coupled receptors (GPCRs) show varying degrees of basal or constitutive activity. This constitutive… Expand
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2011
2011
OBJECTIVE Determine the effects of pimavanserin tartrate [ACP-103; N-(4-flurophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2… Expand
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Highly Cited
2010
Highly Cited
2010
Psychotic symptoms occur in up to 40% of patients with Parkinson's disease (PD). Clozapine and quetiapine, two atypical… Expand
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2008
2008
A potent 5-hydroxytryptamine (5-HT)2A receptor inverse agonist and antagonist, ACP-103 [N-(4-fluorophenylmethyl)-N-(1… Expand
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2008
2008
The mechanisms underlying the clinical properties of atypical antipsychotics have been postulated to be mediated, in part, by… Expand
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2007
2007
Dopamine D(2) receptor antagonism contributes to the therapeutic action of antipsychotic drugs (APDs) but also produces… Expand
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2007
2007
The pharmacokinetics, safety, and tolerability of ACP-103, a selective serotonin 5-HT(2A) receptor inverse agonist, were… Expand
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Highly Cited
2006
Highly Cited
2006
The in vitro and in vivo pharmacological properties of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2… Expand
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Review
2006
Review
2006
  • Claire Roberts
  • Current opinion in investigational drugs
  • 2006
  • Corpus ID: 21495202
ACADIA Pharmaceuticals is developing ACP-103, lead compound in a series of 5-HT2A inverse agonists, as a potential antipsychotic… Expand
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2005
2005
RationalAtypical antipsychotic drugs (APDs) such as clozapine, olanzapine, quetiapine, risperidone, and ziprasidone are serotonin… Expand
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