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ACH 702

Known as: ACH-702, ACH702 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2010-2018
012320102018

Related topics

Related topics

3 relations

Broader (3)

QuinolonesThiazolesTopoisomerase I Inhibitors

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
ACH 702
Quinolones
Thiazoles
Topoisomerase I Inhibitors

Papers overview

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2018
2018
Combinatorial design and virtual screening of potent anti-tubercular fluoroquinolone and isothiazoloquinolone compounds utilizing QSAR and pharmacophore modelling.
The virulence of tuberculosis infections resistant to conventional combination drug regimens cries for the design of potent… (More)
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2013
2013
Intracellular activity of tedizolid phosphate and ACH-702 versus Mycobacterium tuberculosis infected macrophages
Due to the emergency of multidrug-resistant strains of Mycobacterium tuberculosis, is necessary the evaluation of new compounds… (More)
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2012
2012
Bactericidal activity of ACH-702 against nondividing and biofilm Staphylococci.
Many bacterial infections involve slow or nondividing bacterial growth states and localized high cell densities. Antibiotics with… (More)
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2011
2011
In vitro and in vivo profiles of ACH-702, an isothiazoloquinolone, against bacterial pathogens.
ACH-702, a novel isothiazoloquinolone (ITQ), was assessed for antibacterial activity against a panel of Gram-positive and Gram… (More)
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2010
2010
In vitro antituberculosis activities of ACH-702, a novel isothiazoloquinolone, against quinolone-susceptible and quinolone-resistant isolates.
ACH-702 is a new isothiazoloquinolone with potent in vitro and in vivo activities against important bacterial pathogens… (More)
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2010
2010
In vitro activity of a new isothiazoloquinolone, ACH-702, against Mycobacterium tuberculosis and other mycobacteria.
In this work, we describe the activity of ACH-702 against clinical isolates of Mycobacterium tuberculosis and six different… (More)
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2010
2010
In vitro activity of ACH-702, a new isothiazoloquinolone, against Nocardia brasiliensis compared with econazole and the carbapenems imipenem and meropenem alone or in combination with clavulanic acid…
The in vitro activities of ACH-702 and other antimicrobials against 30 Nocardia brasiliensis isolates were tested. The MIC(50… (More)
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