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AC 90179

Known as: AC-90179, AC90179 
 
National Institutes of Health

Papers overview

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2012
2012
Clozapine-Induced Locomotor Suppression is Mediated by 5-HT2A Receptors in the Forebrain
The need for safer, more effective therapeutics for the treatment of schizophrenia is widely acknowledged. To optimally target… Expand
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2009
2009
A Kappa Opioid Model of Atypical Altered Consciousness and Psychosis: U50488, DOI, AC90179 Effects on Prepulse Inhibition and Locomotion in Mice.
Sensorimortor gating and locomotion are behaviors that reflect pre-attentive sensory filtering and higher order, top-down… Expand
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2004
2004
Pharmacological Characterization of AC-90179 [2-(4-Methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist
The primary purpose of the present series of experiments was to characterize the in vitro and in vivo pharmacology profile of 2… Expand
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2003
2003
5-hydroxytryptamine(2A) receptors regulate sympathetic nerves constricting the cutaneous vascular bed in rabbits and rats.
Hyperthermia induced by 3,4-methylenedioxymethamphetamine (MDMA) is partially due to sympathetically-mediated cutaneous… Expand
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Highly Cited
2001
Highly Cited
2001
5-hydroxytryptamine2A receptor inverse agonists as antipsychotics.
We have used a cell-based functional assay to define the pharmacological profiles of a wide range of central nervous system… Expand
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