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National Institutes of Health
Semantic Scholar uses AI to extract papers important to this topic.
Clozapine-Induced Locomotor Suppression is Mediated by 5-HT2A Receptors in the Forebrain
James B. Hanks
Corpus ID: 19355138
The need for safer, more effective therapeutics for the treatment of schizophrenia is widely acknowledged. To optimally target…
A Kappa Opioid Model of Atypical Altered Consciousness and Psychosis: U50488, DOI, AC90179 Effects on Prepulse Inhibition and Locomotion in Mice.
Michael A Ruderman
Journal of young investigators
Corpus ID: 9252521
Sensorimortor gating and locomotion are behaviors that reflect pre-attentive sensory filtering and higher order, top-down…
Pharmacological Characterization of AC-90179 [2-(4-Methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist
S. C. Harvey
Robert E Davis
Journal of Pharmacology and Experimental…
Corpus ID: 12205122
The primary purpose of the present series of experiments was to characterize the in vitro and in vivo pharmacology profile of 2…
5-hydroxytryptamine(2A) receptors regulate sympathetic nerves constricting the cutaneous vascular bed in rabbits and rats.
Corpus ID: 2422133
Hyperthermia induced by 3,4-methylenedioxymethamphetamine (MDMA) is partially due to sympathetically-mediated cutaneous…
5-hydroxytryptamine2A receptor inverse agonists as antipsychotics.
The Journal of pharmacology and experimental…
Corpus ID: 15773694
We have used a cell-based functional assay to define the pharmacological profiles of a wide range of central nervous system…
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