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AC 7700

Known as: AVE8062, Combretastatin A4 Analogue AVE8062, AC7700 
National Institutes of Health

Papers overview

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Review
2014
Review
2014
Antivascular approaches aim to cause rapid and catastrophic shutdown in the vascular function of the tumour, leading to extensive… 
Review
2013
Review
2013
Combretastatin A-4 (CA-4) is an anti-mitotic agent that is gaining rapid recognition among cancer biologists and clinicians as… 
2008
2008
AACR Annual Meeting-- Apr 12-16, 2008; San Diego, CA LB-302 Abstract LB-302 is scheduld in a Late-Breaking Abstract session… 
Review
2007
Review
2007
Vascular disrupting agents (VDAs) are a new class of potential anticancer drugs that selectively destroy tumor vasculature and… 
2006
2006
13074 Background: AVE8062 is a synthetic, water-soluble compound, analog of Combretastatin A4, currently in Phase I clinical… 
Review
2005
Review
2005
Despite extensive research efforts, effective therapies for refractive cancers have not yet been established, and development of… 
2002
2002
AbstractBackground. Unlike the many chemotherapeutic agents that do not effectively stop blood flow or induce necrosis in… 
2001
2001
BACKGROUND Using several transplanted tumors in rats and mice, we have recently shown that the acute extensive necrosis of tumor… 
Highly Cited
1999
Highly Cited
1999
Tubulin binding agents (TBAs) reduce tumor perfusion and inhibit mitosis of tumor cells in solid tumors, but it is not clear… 
1999
1999
The synthesis and antitumor activity of water-soluble amino acid prodrugs of amino-combretastatins were reported. Among the…