ABT-288
National Institutes of Health
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INTRODUCTION
ABT-288 is a highly potent histamine-3 receptor antagonist that has demonstrated pro-cognitive effects in…
BACKGROUND
ABT-288, a highly selective histamine-3 receptor antagonist, demonstrated efficacy across several preclinical…
AIMS
ABT-288 is a potent and selective H3 receptor antagonist with procognitive effects in several preclinical models. In…
Background: ABT-288, a highly selective histamine-3 receptor antagonist, demonstrated efficacy across several preclinical…
AIM
The objective of this work was to characterize the safety, tolerability and pharmacokinetics of ABT-288, a highly selective…
Histamine H3 receptor antagonists, such as ABT-288, have been shown to possess cognitive-enhancing and wakefulness-promoting…
Blockade of the histamine H3 receptor (H3R) enhances central neurotransmitter release, making it an attractive target for the…