ABCB4 wt Allele

Known as: ABC21, Multidrug Resistance 3 Gene, GBD1 
Human ABCB4 wild-type allele is located in the vicinity of 7q21.1 and is approximately 79 kb in length. This allele, which encodes multidrug… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
ATP-binding cassette (ABC) efflux transporters are expressed in the human placenta where they are thought to help protect the… (More)
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Highly Cited
2003
Highly Cited
2003
The human multidrug resistance gene MDR3 encodes a P-glycoprotein that belongs to the ATP-binding cassette transporter family… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND & AIMS Many studies indicate that gallstone susceptibility has genetic components. MDR3 is the phosphatidylcholine… (More)
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Highly Cited
2001
Highly Cited
2001
This investigation describes the expression and interindividual variability in transcript levels of multiple drug efflux systems… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND & AIMS We have specified the features of progressive familial intrahepatic cholestasis type 3 and investigated in 31… (More)
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Highly Cited
2001
Highly Cited
2001
The multidrug resistance (MDR) phenotype is a major cause of cancer treatment failure. Here the expressions of 4224 genes were… (More)
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Highly Cited
2000
Highly Cited
2000
Intrahepatic cholestasis of pregnancy (ICP) is a liver disease of pregnancy with serious consequences for the mother and fetus… (More)
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Highly Cited
2000
Highly Cited
2000
Tumor cells may display a multidrug resistance phenotype by overexpression of ATP binding cassette transporter genes such as… (More)
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Highly Cited
1999
Highly Cited
1999
Background: Laparoscopic skill was measured objectively through a series of seven tasks in an inanimate laparoscopic simulator… (More)
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Highly Cited
1993
Highly Cited
1993
We studied 53 patients with B-cell chronic lymphocytic leukemia (B-CLL) and found mutations of the p53 gene in 15%. Patients with… (More)
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