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A 83586C

Known as: A 83586 C, A-83586C, A83586C 
National Institutes of Health

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Related topics

1 relation

Broader (1)

Depsipeptides

Papers overview

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2009
2009
Synthesis of A83586C analogs with potent anticancer and beta-catenin/ TCF4/osteopontin inhibitory effects and insights into how A83586C modulates E2Fs and pRb.
The synthesis of three potent new antitumor agents is described: the A83586C-citropeptin hybrid (1), the A83586C-GE3 hybrid (2… 
2009
2009
Molecules of the A83586C-Azinothricin-Kettapeptin and Agelastatin A Class; Their Synthesis, Mechanisms of Antitumour Action, and Potential for Counteracting β-Catenin Driven Cell Signalling
2008
2008
Pharmacological actions of a new synthetic cyclodepsipeptide, the A83586C-citropeptin hybrid, on complement C5a and G-Proteins
1 Department of Pharmacology, University College London, London WC1E 6BT, United Kingdom, Fax: +44 20 7679 7298, e-mail: e.assem… 
2008
2008
Synthetic studies on molecules related to the azinothricin family and allopumiliotoxin 339A
The Azinothricin family of compounds are based on a cyclodepsipeptide core and were first encountered in the late 1980s. Most of… 
2005
2005
Synthetic studies on the A83586C/GE3 family of antitumour antibiotics.
The A83586C/GE3 class of cyclodepsipeptides are a family of antitumour antibiotics whose antitumour properties have been… 
2002
2002
Synthesis of an L-proline modified mimetic of the A83586C antitumour cyclodepsipeptide.
A mimetic of the A83586C cyclodepsipeptide has been synthesised via a three-segment coupling protocol involving dipeptides 9, 8… 
2000
2000
Synthetic studies on the A83586C and bryostatin antitumor macrolides and the monamycin antibiotics
Abstract After a brief summary of our asymmetric total syntheses of A83586C and 4-epi-A83586C, we will go on to describe some of… 
1997
1997
Biosynthetic origin of the tetrahydropyranyl side chain of verucopeptin
1990
1990
Structural studies on new depsipeptide antibiotics, variapeptin and citropeptin.
Variapeptin and citropeptin were found as novel hexadepsipeptide antibiotics produced by Streptomyces variabilis and Streptomyces… 
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