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A 77636

Known as: A-77636, A77636 
 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

AdamantaneAntiparkinson AgentsBenzopyransDopamine Agonists
analogs & derivatives

Papers overview

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2015
2015
The role of dopamine D1 receptor transmission in effort-related choice behavior: Effects of D1 agonists
Mesolimbic dopamine (DA), particularly in the nucleus accumbens, is a critical component of the brain circuitry involved in… Expand
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2010
2010
Amelioration of ketamine-induced working memory deficits by dopamine D1 receptor agonists
RationaleKetamine has been used in humans to model cardinal symptoms of schizophrenia, including working memory impairments and… Expand
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2002
2002
Comparison of interactions of D1-like agonists, SKF 81297, SKF 82958 and A-77636, with cocaine: locomotor activity and drug discrimination studies in rodents
Rationale: Recent data suggest that dopamine (DA) D1-like receptor full agonists may be potential pharmacotherapeutic agents for… Expand
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2001
2001
Rewarding and locomotor-activating effects of direct dopamine receptor agonists are augmented by chronic food restriction in rats
Abstract. Rationale: Previous studies indicate that chronic food restriction augments the rewarding and motor-activating effects… Expand
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2000
2000
Increased behavioral response to dopaminergic stimulation of the subthalamic nucleus after nigrostriatal lesions.
Local infusions of the nonselective dopaminergic agonist apomorphine into the subthalamic nucleus of rats has been shown to… Expand
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1999
1999
Actions of the D1 agonists A-77636 and A-86929 on locomotion and dyskinesia in MPTP-treated L-dopa-primed common marmosets
Abstract Common marmosets show parkinsonian motor deficits following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP… Expand
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1998
1998
Effects of full D1 dopamine receptor agonists on firing rates in the globus pallidus and substantia nigra pars compacta in vivo: tests for D1 receptor selectivity and comparisons to the partial…
Many studies have used the D1 agonist SKF 38393 to characterize D1 receptor influences on firing rates in basal ganglia nuclei in… Expand
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1996
1996
Persistent activation of the dopamine D1 receptor contributes to prolonged receptor desensitization: studies with A-77636.
A-77636 is a dopamine (DA) D1 receptor-selective agonist that was previously shown to elicit beneficial responses in animal… Expand
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Highly Cited
1995
Highly Cited
1995
Chronic L-DOPA administration induces dyskinesias in the 1-methyl-4- phenyl-1,2,3,6-tetrahydropyridine-treated common marmoset (Callithrix Jacchus).
Dyskinesias occur in the majority of patients with Parkinson's disease chronically treated with L-DOPA and also occur in several… Expand
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1992
1992
A-77636: a potent and selective dopamine D1 receptor agonist with antiparkinsonian activity in marmosets.
A-77636, ((1R,3S) 3-(1'-adamantyl)-1-aminomethyl-3,4-dihydro-5,6-dihydroxy-1H-2-benz opyran hydrochloride), is a selective… Expand
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