FAQ

A 77636

Known as: A-77636, A77636 
 

Topic mentions per year

Topic mentions per year

1992-2016
024619922016

Related topics

Related topics

4 relations

Broader (4)

AdamantaneAntiparkinson AgentsBenzopyransDopamine Agonists

Related mentions per year

Related mentions per year

1954-2018
1960198020002020
A 77636
Dopamine Agonists
Antiparkinson Agents
Adamantane
Benzopyrans

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Amelioration of ketamine-induced working memory deficits by dopamine D1 receptor agonists
Ketamine has been used in humans to model cardinal symptoms of schizophrenia, including working memory impairments and behavioral… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2006
2006
Differential ability of D1 and D2 dopamine receptor agonists to induce and modulate expression and reinstatement of cocaine place preference in rats
D1-Like agonists are self-administered by drug-naive animals, whereas D2-like agonists reinstate cocaine-seeking behavior, but… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2005
2005
Differential activation of adenylate cyclase and receptor internalization by novel dopamine D1 receptor agonists.
Structurally dissimilar dopamine D(1) receptor agonists were compared with dopamine in their ability to activate adenylate… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
2001
2001
Rewarding and locomotor-activating effects of direct dopamine receptor agonists are augmented by chronic food restriction in rats
Rationale: Previous studies indicate that chronic food restriction augments the rewarding and motor-activating effects of diverse… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1998
1998
Homologous desensitization of the D1A dopamine receptor: efficacy in causing desensitization dissociates from both receptor occupancy and functional potency.
The role of drug efficacy in agonist-induced desensitization was studied in C-6 glioma cells transfected with the monkey dopamine… (More)
  • figure 2
  • table 1
  • figure 1
  • table 2
  • table 3
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Dose-dependent effects of the dopamine D1 receptor agonists A77636 or SKF81297 on spatial working memory in aged monkeys.
With advancing age, monkeys develop deficits in spatial working memory resembling those induced by lesions of the prefrontal… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1996
1996
Persistent activation of the dopamine D1 receptor contributes to prolonged receptor desensitization: studies with A-77636.
A-77636 is a dopamine (DA) D1 receptor-selective agonist that was previously shown to elicit beneficial responses in animal… (More)
Is this relevant?
1996
1996
Conformational analysis of D1 dopamine receptor agonists: pharmacophore assessment and receptor mapping.
Compute-aided conformational analysis was used to characterize the agonist pharmacophore for D1 dopamine receptor recognition and… (More)
Is this relevant?
1994
1994
The potent and selective dopamine D1 receptor agonist A-77636 increases cortical and hippocampal acetylcholine release in the rat.
The effects of systemic administration of the full dopamine D1 receptor agonist A-77636 on acetylcholine release in rat frontal… (More)
Is this relevant?
1992
1992
A-77636: a potent and selective dopamine D1 receptor agonist with antiparkinsonian activity in marmosets.
A-77636, ((1R,3S) 3-(1'-adamantyl)-1-aminomethyl-3,4-dihydro-5,6-dihydroxy-1H-2-benz opyran hydrochloride), is a selective… (More)
Is this relevant?