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9-hydroxyellipticine
Known as:
NSC 210717
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Antimetabolites, Antineoplastic
Ellipticines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Microbial transformation of azacarbazoles X: Regioselective hydroxylation of 5,11-dimethyl-5H-indolo [2,3-b]quinoline, a novel DNA topoisomerase II inhibitor, by Rhizopus arrhizus
W. Peczyńska‐Czoch
,
J. Osiadacz
,
Ł. Kaczmarek
,
T. Zal
Biotechnology Letters
2004
Corpus ID: 40124225
SummaryMicrobial transformation of cytotoxic 5,11-dimethyl-5H-indolo[2,3-b]quinoline (a compound displaying antitumor activity…
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1987
1987
[Demonstration of an oxidative biotransformation of 9-methoxyellipticine. Comparison with the case of 9-hydroxyellipticine].
Y. Braham
,
G. Meunier
,
B. Meunier
Comptes rendus de l'Academie des sciences. Serie…
1987
Corpus ID: 42340500
Evidences for the formation of the glutathione-hydroxyellipticine adduct during the rat metabolism of 9-methoxyellipticine are…
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1983
1983
Autoxidation of the antitumor drug 9-hydroxyellipticine and its derivatives.
C. Auclair
,
K. Hyland
,
C. Paoletti
Journal of Medicinal Chemistry
1983
Corpus ID: 12734483
In aqueous solution and using molecular oxygen as electron acceptor, the antitumor drug 9-hydroxyellipticine (9-OH-E) undergoes a…
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1983
1983
Interactions between 9-hydroxyellipticine and X rays on mammalian cell survival in vitro.
S. Michel
,
J. Huet
,
F. Laval
Radiation Research
1983
Corpus ID: 20961581
Incubation with 9-hydroxyellipticine (9-OH-E) decreases the survival of X-irradiated CHO cells. The survival decreases in the…
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1982
1982
The mutagenicity of 9-hydroxyellipticine and its induction of cytochrome P-448 activity in rat liver microsomes.
C. Phillipson
,
P. Godden
,
C. Ioannides
,
D. Parke
Carcinogenesis
1982
Corpus ID: 40211575
Administration of a single dose of the inhibitor of the hepatic mixed function oxidases, 9-hydroxyellipticine (9-OHE), resulted…
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Review
1981
Review
1981
Ellipticine, 9-hydroxyellipticine, and 9-hydroxyellipiticinum: some biochemical properties of possible pharmacologic significance.
C. Paoletti
,
C. Auclair
,
P. Lesca
,
J. Tocanne
,
C. Malvy
,
M. Pinto
Cancer treatment reports
1981
Corpus ID: 35683463
Ellipticine, 5,11-dimethyl-(6H)-pyrido-(4,3,b)-carbazole (NSC 71795) is a potent cytotoxic and antitumor agent. Several of its…
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1981
1981
Influence of inducers of monooxygenases on cytotoxic efficiency of ellipticine on leukemia L1210 cells.
P. Lesca
,
B. Monsarrat
,
S. Cros
,
C. Paoletti
Journal of the National Cancer Institute
1981
Corpus ID: 31287744
The effects of some inducers of microsomal cytochrome P450-dependent monooxygenases on the metabolic bioactivation and the…
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1980
1980
In vivo effects of intercalating and nonintercalating drugs on the tertiary structure of kinetoplast deoxyribonucleic acid.
J. Bénard
,
G. Riou
Biochemistry
1980
Corpus ID: 7161380
The kinetoplast DNA (kDNA) of cultured Trypanosoma cruzi consists mostly in a large network of numerous minicircular molecules…
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1976
1976
Antitumor activity of 9-hydroxyellipticine (NSC 210717) ON L1210 mouse leukemia and the effect of route of injection.
J. Le Pecq
,
C. Gosse
,
Nguyên-Dat-Xuong
,
S. Cros
,
C. Paoletti
Cancer Research
1976
Corpus ID: 8574987
The antitumor activity of a new derivative of ellipticine, 9-hydroxyellipticine (NSC 210717), was studied using L1210 mouse…
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1976
1976
Inhibition of estrogen-receptor-DNA interaction by intercalating drugs.
J. André
,
A. Pfeiffer
,
H. Rochefort
Biochemistry
1976
Corpus ID: 11407008
Ethidium bromide, an intercalating drug, was shown to inhibit the in vitro DNA binding of the uterine estradiol-receptor complex…
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