9-hydroxyellipticine

Known as: NSC 210717 
 

Topic mentions per year

Topic mentions per year

1974-2012
024619742012

Papers overview

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2004
2004
Ellipticine is an antineoplastic agent, the mode of action of which is considered to be based on DNA intercalation and inhibition… (More)
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1999
1999
Wild-type p53 causes cell-cycle arrest at late G1 phase and induction of apoptosis by up- regulation of waf1 and bax… (More)
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1998
1998
There is increasing interest in identifying potent inhibitors of telomerase because the enzyme plays a crucial role in the… (More)
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1995
1995
Abnormality of p53, a tumor suppressor gene, is considered to be a potential cause of malignancy. We found that ellipticine and 9… (More)
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1989
1989
We have previously shown that Chinese hamster lung cells resistant to 9-hydroxyellipticine, DC-3F/9-OH-E, display multiple… (More)
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Highly Cited
1989
Highly Cited
1989
Tyrosine phosphorylation plays a crucial role in cell proliferation and cell transformation which suggests that tyrosine kinase… (More)
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1988
1988
We have isolated a Chinese hamster lung cell line resistant to 9-hydroxyellipticine (DC-3F/9-OH-E) which is also cross-resistant… (More)
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1984
1984
Development of resistance to 9-hydroxyellipticine in Chinese hamster lung cells is associated with a loss of oncogenic potential… (More)
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1981
1981
Hydroxylation in position 9 (see Table I) of various antitumor drugs derived from ellipticine results, in most cases, in the… (More)
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1974
1974
The designing of DNA intercalating drugs with high DNA affinity in the series of ellipticine has led to a new antitumoral agent… (More)
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