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9-deoxo-31-O-demethyl-FK506

Known as: 9-deoxo-31-O-demethyl-FK-506, 9-deoxo-31-O-demethylFK506 
 
National Institutes of Health

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2 relations

Broader (1)

Tacrolimus
analogs & derivatives

Papers overview

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2010
2010
Demethyl fruticulin A (SCO-1) causes apoptosis by inducing reactive oxygen species in mitochondria.
Demethyl fruticulin A (SCO-1) is a compound found in Salvia corrugata leaves. SCO-1 was reported to induce anoikis in cell lines… Expand
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2010
2010
Identification of rat urinary metabolites of rifabutin using LC-MSn and LC-HR-MS.
Rifabutin, an anti-mycobacterial agent, is reported to be extensively metabolized in vivo into more than 20 biotransformation… Expand
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2004
2004
The metabolism of pyrazoloacridine (NSC 366140) by cytochromes p450 and flavin monooxygenase in human liver microsomes.
Pyrazoloacridine (PZA) is an experimental antitumor agent presently under investigation for treatment of solid tumors on the… Expand
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2002
2002
Total synthesis of deamido bleomycin a(2), the major catabolite of the antitumor agent bleomycin.
Metabolic inactivation of the antitumor antibiotic bleomycin is believed to be mediated exclusively via the action of bleomycin… Expand
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2002
2002
In vitro metabolism of a novel phosphodiesterase-5 inhibitor DA-8159 in rat liver preparations using liquid chromatography/electrospray mass spectrometry.
The in vitro metabolism of a new erectogenic, DA-8159, has been studied by LC with UV detection and on-line LC-electrospray mass… Expand
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2001
2001
Synthesis of variously oxidized abietane diterpenes and their antibacterial activities against MRSA and VRE.
Variously oxidized 12 natural abietanes, 6,7-dehydroferruginol methyl ether (3), ferruginol (5), 11-hydroxy-12-oxo-7,9(11),13… Expand
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1999
1999
Yeast and rat Coq3 and Escherichia coli UbiG polypeptides catalyze both O-methyltransferase steps in coenzyme Q biosynthesis.
Ubiquinone (coenzyme Q or Q) is a lipid that functions in the electron transport chain in the inner mitochondrial membrane of… Expand
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1996
1996
Clinical and pharmacokinetic study of oral NK611, a new podophyllotoxin derivative
Abstract NK611 is a novel water-soluble podophyllotoxin derivative that has comparable antitumour activity but higher potency and… Expand
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1985
1985
Receptors for 3H-octopamine in the adult firefly light organ.
3H-Octopamine binds reversibly and with high affinity to sites on adult firefly light organ membranes. The binding is… Expand
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Highly Cited
1977
Highly Cited
1977
Plasma pharmacokinetics of adriamycin and its metabolites in humans with normal hepatic and renal function.
A new, nondestructive, plasma extraction technique ultilizing chloroform:isopropyl alcohol (1:1) and ammonium sulfate saturation… Expand
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