Semantic Scholar uses AI to extract papers important to this topic.
The mitoxantrone resistance (MXR) gene encodes a recently characterized ATP-binding cassette half-transporter that confers… Expand We have previously demonstrated that calpain is responsible for the cleavage of Bax, a proapoptotic protein, during drug-induced… Expand We investigated the relationship among chemosensitivity to drug-induced apoptosis in vitro, the presence of p53 gene mutations… Expand BACKGROUND
Camptothecins belong to a group of anticancer agents with a unique mechanism of action: poisoning of eukaryotic DNA… Expand 1. Stretch‐activated anion currents were studied in sino‐atrial and atrial cells using the whole‐cell patch clamp technique. With… Expand In order to understand the high efficacy of camptothecin derivatives against human colon tumor xenografts in nude mice, we have… Expand Drug development is needed to improve chemotherapy of patients with locally advanced or metastatic colon carcinoma, who otherwise… Expand 1. Currents evoked by elevated intracellular free Ca2+ in Xenopus laevis oocytes were studied using the two‐electrode voltage… Expand Interactions between calmodulin (CaM) and several hydrophobic fluorescent probes were characterized in order to determine if CaM… Expand 25 aromatic carboxylic acids which are analogs of benzoic acid were tested in the rat diaphragm preparation for effects on… Expand