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8-oxodGTP

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Cellular homeostasis is dependent on a balance between DNA damage and DNA repair mechanisms. Cells are constantly assaulted by… Expand
2007
2007
In the presence of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) damage, many DNA polymerases exhibit a dual coding potential… Expand
Highly Cited
2006
Highly Cited
2006
To assess the role of oxidative stress on the replication of mitochondrial DNA, we examined the kinetics of incorporation of 8… Expand
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Review
2003
Review
2003
Genomes are damaged by spontaneous decay, chemicals, radiation and replication errors. DNA damage may cause mutations resulting… Expand
Highly Cited
2002
Highly Cited
2002
Mismatch repair (MMR) corrects replication errors. It requires the MSH2, MSH6, MLH1, and PMS2 proteins which comprise the… Expand
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Highly Cited
2000
Highly Cited
2000
To understand how the active site of a DNA polymerase might modulate the coding of 8-oxo-7,8-dihydrodeoxyguanine (8-oxodG), we… Expand
Highly Cited
1998
Highly Cited
1998
8-Oxoguanine (8-oxoG), induced by reactive oxygen species (ROS) and ionizing radiation, is arguably the most important mutagenic… Expand
Highly Cited
1996
Highly Cited
1996
We describe a new method for random mutagenesis of DNA based on the use of a mixture of triphosphates of nucleoside analogues… Expand
Highly Cited
1992
Highly Cited
1992
8-Oxoguanine nucleotide can pair with cytosine and adenine nucleotides at almost equal efficiencies. Once 8-oxodGTP is formed in… Expand