8-oxo-7-hydrodeoxyguanosine

Known as: 7,8-dihydro-8-oxo-2'-deoxyguanosine, 8-Oxo-7,8-dihydro-2'-deoxyguanosine, 8-OH-dG 
A major spontaneous oxidized derivative of 2'-deoxyguanosine and a biomarker of oxidative DNA damage. 8-hydroxy-2'-deoxyguanosine (8-oxo-dG) is… (More)
National Institutes of Health

Papers overview

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Review
2009
Review
2009
There is extensive experimental evidence that oxidative damage permanently occurs to lipids of cellular membranes, proteins, and… (More)
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Review
2004
Review
2004
The generation of reactive oxygen species may be both beneficial to cells, performing a function in inter- and intracellular… (More)
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Highly Cited
2004
Highly Cited
2004
Although inflammation and protease/antiprotease imbalance have been postulated to be critical in cigarette smoke-induced (CS… (More)
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Review
2004
Review
2004
Reactive oxygen species (ROS) produced either endogenously or exogenously can attack lipid, protein and nucleic acid… (More)
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Review
1997
Review
1997
8-hydroxy-2'-deoxyguanosine (8-OH-dG) was first reported in 1984 as a major form of oxidative DNA damage product by heated sugar… (More)
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Highly Cited
1997
Highly Cited
1997
The etiology of the selective neuronal death that occurs in Huntington's disease (HD) is unknown. Several lines of evidence… (More)
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Highly Cited
1996
Highly Cited
1996
 
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Highly Cited
1994
Highly Cited
1994
Oxidative damage to DNA may play a role in both normal aging and in neurodegenerative diseases. We examined whether Alzheimer's… (More)
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Highly Cited
1991
Highly Cited
1991
OXIDATIVE damage to DNA, reflected in the formation of 8-oxo- 7-hydrodeoxyguanosine (8-oxodG)1,2, may be important in mutagenesis… (More)
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Highly Cited
1988
Highly Cited
1988
Oxidative damage to DNA can be caused by excited oxygen species, which are produced by radiation or are by-products of aerobic… (More)
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