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8-nitro-2'-deoxyguanosine

National Institutes of Health

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2 relations

Broader (1)

Deoxyguanosine
analogs & derivatives

Papers overview

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2012
2012
Base-pairing preferences, physicochemical properties and mutational behaviour of the DNA lesion 8-nitroguanine†
8-Nitro-2′-deoxyguanosine (8-nitrodG) is a relatively unstable, mutagenic lesion of DNA that is increasingly believed to be… 
Highly Cited
2005
Highly Cited
2005
Miscoding events during DNA synthesis past the nitration-damaged base 8-nitroguanine.
8-Nitro-2'-deoxyguanosine (8-NO(2)-dG) DNA adducts are induced by the reactive nitrogen species and may be associated with the… 
2002
2002
Photochemically catalyzed generation of site-specific 8-nitroguanine adducts in DNA by the reaction of long-lived neutral guanine radicals with nitrogen dioxide.
A novel photochemical approach is described for synthesizing site-specific 8-nitro-2'-deoxyguanosine (8-nitro-dG) adducts DNA… 
Highly Cited
1999
Highly Cited
1999
8-Nitro-2'-deoxyguanosine, a specific marker of oxidation by reactive nitrogen species, is generated by the myeloperoxidase-hydrogen peroxide-nitrite system of activated human phagocytes.
Reactive intermediates generated by phagocytes damage DNA and may contribute to the link between chronic inflammation and cancer… 
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