8-mercaptoguanosine
National Institutes of Health
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In the present paper, we investigated the requirements for the induction of IgE responses in murine B cells stimulated via…
We have shown previously that pneumococcal polysaccharides behave as human T cell-independent type 2 Ag. When cultured in vitro…
In previous studies it has been demonstrated that a T cell-like differentiation signal is transmitted by C8-substituted guanine…
The current studies were undertaken to explore the regulatory effects of macrophages and their soluble products on B cell…
B lymphocytes require a source of T cell-like help to produce antibody to T cell-dependent antigens. T cell-derived lymphokines…
8-Mercaptoguanosine (8sGuo) has been reported to enhance responses of normal mice to the type 2 antigen trinitrophenol (TNP…
Lymphocyte proliferation and differentiation result from ordered cellular interactions governed by soluble products (lymphokines…
Abstract The contribution of T cells to potentiation of humoral immunity by the C8-substituted guanine ribonucleosides and the…
The mechanism by which increased numbers of antigen-responsive B cells are generated in the presence of antigen and the C8…
Lymphocyte activation, whether specific or nonspecific, is generally conceptualized as initiated by the binding of an activating…