8-hydroxywarfarin

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1969-2018
01219692018

Papers overview

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2012
2012
Coumadin (R-, S-warfarin) is a challenging drug to accurately dose, both initially and for maintenance, because of its narrow… (More)
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2012
2012
Coumadin (R/S-warfarin) is a highly efficacious and widely used anticoagulant; however, its highly variable metabolism remains an… (More)
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2008
2008
Recent studies show that the extrahepatic human UDP-glucuronosyltransferase (UGT)1A10 is capable of phase II glucuronidation of… (More)
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2005
2005
An assay comprising two simple, selective and isocratic HPLC methods with UV detection was developed and validated for measuring… (More)
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2001
2001
A sensitive assay using high-performance liquid chromatography tandem mass spectrometry (MS/MS) has been established for the… (More)
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1993
1993
The regio- and stereoselectivity of warfarin metabolism have been used to assess structure-function relationships of human P4502C… (More)
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1992
1992
We used adult rat hepatocytes in primary culture (HPC) as a model system to study the hepatic phase II metabolism of the… (More)
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1991
1991
Healthy men were administered i.v. racemic warfarin, S-warfarin or R-warfarin on two occasions, once in the drug-free state and… (More)
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1989
1989
The oxidative biotransformation of (R)- and (S)-warfarin was studied in human liver microsomes to determine whether an in vitro… (More)
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1987
1987
The mechanism of the drug interaction in humans between warfarin and rifampin was investigated by monitoring the elimination… (More)
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