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8-hydroxyfuranocoumarin 8-O-methyltransferase activity

Known as: S-adenosyl-L-methionine:8-hydroxyfuranocoumarin 8-O-methyltransferase activity, xanthotoxol methyltransferase activity, furanocoumarin 8-O-methyl-transferase activity 
Catalysis of the reaction: S-adenosyl-L-methionine + xanthotoxol = S-adenosyl-L-homocysteine + xanthotoxin. Xanthotoxol is also known as 8… Expand
National Institutes of Health

Papers overview

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2018
2018
Abstract Imperation analogs have the furanocoumarin skeleton, with the isopentenyl group, which displayed significant… Expand
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2017
2017
The presence of multidrug resistance (MDR) in tumor cells is considered as the major cause of failure of cancer chemotherapy. The… Expand
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2017
2017
A series of linear furanocoumarins with different substituents have been designed and synthesized. Their structures were… Expand
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2014
2014
Background: Furanocoumarin imperatorin is a major active component of Angelica dahurica root extracts exhibiting analgesic… Expand
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2014
2008
2008
Cyclic nucleotide phosphodiesterases (PDEs) comprise a superfamily of enzymes that serve as drug targets in many human diseases… Expand
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2006
2006
Furanocoumarins have been shown to inhibit CYP3A4 in vitro with varying degrees of potency. In this study, we report the effects… Expand
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1990
1990
The parsnip webworm,Depressaria pastinacella, feeds on plants containing high concentrations of furanocoumarins. compounds toxic… Expand
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1986
1986
FourEscherichia coli strains carrying all the possible combinations of genes controlling sensitivity to near-UV (NUV;nur… Expand
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