8-hydroxyefavirenz

 

Topic mentions per year

Topic mentions per year

2003-2018
012320032018

Papers overview

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2014
2014
The purpose of this study was to determine the demographic and pharmacogenetic covariates that influence the disposition of… (More)
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2012
2012
Despite combination antiretroviral therapies (cARTs), a significant proportion of HIV-infected patients develop HIV-associated… (More)
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2012
2012
The mechanism by which CYP2B6*6 allele alters drug metabolism in vitro and in vivo is not fully understood. To test the… (More)
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2011
2011
Chronic use of efavirenz (EFV) has been linked to incidences of hepatotoxicity in patients receiving EFV to treat HIV-1. While… (More)
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2011
2011
We performed a prospective comparative study to examine, from a pharmacogenetics perspective, the effect of rifampicin (RIF) on… (More)
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Highly Cited
2010
Highly Cited
2010
Efavirenz primary and secondary metabolism was investigated in vitro and in vivo. In human liver microsome (HLM) samples, 7- and… (More)
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2010
2010
We investigated the influence of gender and pharmacogenetic variations on long-term efavirenz autoinduction and disposition among… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVES To determine the influence of cytochrome P450 2B6 (CYP2B6) genotype on the rate of oxidative efavirenz metabolism in… (More)
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2006
2006
Efavirenz is a non-nucleoside human immunodeficiency virus (HIV)-1 reverse transcriptase inhibitor used in combination therapy to… (More)
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Highly Cited
2003
Highly Cited
2003
We used human liver microsomes (HLMs) and recombinant cytochromes P450 (P450s) to identify the routes of efavirenz metabolism and… (More)
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