8-deazafolic acid

National Institutes of Health

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1981

1981

New synthesis of N-[4-[[(2-amino-4(3H)-oxopyrido[3,2-d]pyrimidin-6-yl)methyl]amino]benzoyl]-L-glutamic acid (8-deazafolic acid) and the preparation of some 5,6,7,8-tetrahydro derivatives.

C. Temple, C. L. Kussner, J. Rose, D. Smithers, L. L. Bennett, J. Montgomery
Journal of medicinal chemistry
1981
Corpus ID: 23624547

Previously, 8-deazafolic acid (17) was shown to be a potent inhibitor of the folate-dependent bacteria, Streptococcus faecium…

Highly Cited

1974

Highly Cited

1974

Antimicrobial activity of 8-deazafolic acid.

J. Degraw, R. Kisliuk, Y. Gaumont, C. Baugh
Journal of medicinal chemistry
1974
Corpus ID: 10367908