8-chloro-cyclic adenosine monophosphate

Known as: 8-chloroadenosine 3',5'-cyclic monophosphate, cAMP, 8-Chloro Cyclic AMP 
An antimetabolite and a chlorine derivative of the intracellular secondary messenger, cyclic adenosine 3,5-monophosphate (cAMP), with potential… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1940-2017
01000200019402016

Papers overview

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Review
2018
Review
2018
The endothelial barrier consists of intercellular contacts localized in the cleft between endothelial cells, which is covered by… (More)
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Highly Cited
2006
Highly Cited
2006
While bile acids (BAs) have long been known to be essential in dietary lipid absorption and cholesterol catabolism, in recent… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Among the many adipocyte-derived endocrine factors, we found an adipocyte-derived plasma protein, adiponectin, that… (More)
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Highly Cited
1998
Highly Cited
1998
Rap1 is a small, Ras-like GTPase that was first identified as a protein that could suppress the oncogenic transformation of cells… (More)
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1997
1997
8-Chloro-adenosine, the dephosphorylated metabolite of the antineoplastic agent 8-chloro-cyclic AMP, has been proposed to act on… (More)
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Highly Cited
1994
Highly Cited
1994
The cAMP-responsive element-binding protein (CREB) has been implicated in the activation of protein synthesis required for long… (More)
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Highly Cited
1993
Highly Cited
1993
CYCLIC AMP-regulated gene expression frequently involves a DNA element known as the cAMP-regulated enhancer (CRE)1–4. Many… (More)
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Highly Cited
1989
Highly Cited
1989
In this paper, we demonstrate that phosphorylation of CREB at Ser-133 is induced 6-fold in vivo, following treatment of PC12… (More)
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Highly Cited
1987
Highly Cited
1987
Tyrosine-specific protein kinase activity of the epidermal growth factor (EGF) receptor, pp60v-src and pp110gag-fes was inhibited… (More)
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Highly Cited
1970
Highly Cited
1970
A simple and sensitive assay for adenosine 3':5'-cyclic monophosphate (cAMP) has been developed that is based on competition for… (More)
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