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8-chloro-cyclic adenosine monophosphate

Known as: 8-chloroadenosine 3',5'-cyclic monophosphate, cAMP, 8-Chloro Cyclic AMP 
An antimetabolite and a chlorine derivative of the intracellular secondary messenger, cyclic adenosine 3,5-monophosphate (cAMP), with potential… Expand
National Institutes of Health

Papers overview

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Review
1999
Review
1999
It is now nearly 5 years since the last of the currently recognised 5-HT receptors was identified in terms of its cDNA sequence… Expand
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Highly Cited
1998
Highly Cited
1998
Rap1 is a small, Ras-like GTPase that was first identified as a protein that could suppress the oncogenic transformation of cells… Expand
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Highly Cited
1994
Highly Cited
1994
The cAMP-responsive element-binding protein (CREB) has been implicated in the activation of protein synthesis required for long… Expand
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Highly Cited
1993
Highly Cited
1993
CYCLIC AMP-regulated gene expression frequently involves a DNA element known as the cAMP-regulated enhancer (CRE)1–4. Many… Expand
Highly Cited
1989
Highly Cited
1989
In this paper, we demonstrate that phosphorylation of CREB at Ser-133 is induced 6-fold in vivo, following treatment of PC12… Expand
Highly Cited
1987
Highly Cited
1987
Tyrosine-specific protein kinase activity of the epidermal growth factor (EGF) receptor, pp60v-src and pp110gag-fes was inhibited… Expand
Highly Cited
1987
Highly Cited
1987
It has been suggested that the proto-oncogenes c-fos and c-myc participate in the control of genetic events which lead to the… Expand
Review
1987
Review
1987
Pentoxifylline (oxpentifylline) is an orally active haemorheological agent for the treatment of peripheral vascular disease… Expand
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Highly Cited
1984
Highly Cited
1984
Naphthalenesulfonamides such as N-(6-amino-hexyl)-5-chloro-1-naphthalenesulfonamide (W-7) are potent calmodulin (CaM) antagonists… Expand
Highly Cited
1970
Highly Cited
1970
  • A. Gilman
  • Proceedings of the National Academy of Sciences…
  • 1970
  • Corpus ID: 38577379
A simple and sensitive assay for adenosine 3':5'-cyclic monophosphate (cAMP) has been developed that is based on competition for… Expand
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