8-(4-sulfophenyl)theophylline

BACKGROUND Adenosine inhibits proliferation of cardiac fibroblasts and hypertrophy of cardiomyocytes, both of which may play… Expand

PURPOSE Because of the high incidence of pharmacoresistance in the treatment of epilepsy (20-30%), alternative treatment… Expand

BACKGROUND Recent studies in vitro have demonstrated that endothelium-derived hydrogen peroxide (H2O2) is an endothelium-derived… Expand

The genesis of the ischaemia intolerant phenotype in aged myocardium is poorly understood. We tested the hypothesis that impaired… Expand

1. In anaesthetized rats, we have examined the role of adenosine in vasodilatation evoked in the cerebral cortex by systemic… Expand

Activation of the adenosine receptor, protein kinase C (PKC), and the ATP-sensitive potassium (KATP) channel is known to induce… Expand

The effects of intrathecally delivered adenosine agonists on allodynia induced by L5/L6 spinal nerve ligation in rats with lumbar… Expand

The effects of intraperitoneal (I.P.), intracerebroventricular (ICV) and intrathecal (IT) opiates were studied in the rat… Expand

Activation of the cerebellar parallel fibers (PF) releases glutamate and leads to depolarization of Purkinje cells and… Expand

Nociceptive neurons in the dorsal horn of the cat spinal cord are depressed by vibration applied to the ipsilateral hind limb… Expand