8-(4-sulfophenyl)theophylline

Summary:  Purpose: Because of the high incidence of pharmacoresistance in the treatment of epilepsy (20–30%), alternative… Expand

Background—Recent studies in vitro have demonstrated that endothelium-derived hydrogen peroxide (H2O2) is an endothelium-derived… Expand

The genesis of the ischaemia intolerant phenotype in aged myocardium is poorly understood. We tested the hypothesis that impaired… Expand

Activation of the adenosine receptor, protein kinase C (PKC), and the ATP-sensitive potassium (KATP) channel is known to induce… Expand

The effects of intrathecally delivered adenosine agonists on allodynia induced by L5/L6 spinal nerve ligation in rats with lumbar… Expand

The effects of intraperitoneal (I.P.), intracerebroventricular (ICV) and intrathecal (IT) opiates were studied in the rat… Expand

1 ADP‐dependent platelet aggregation is mediated by the P2T‐purinoceptor and is specifically inhibited by ATP, which is a… Expand

1 The Langendorff heart preparation was used to investigate the mechanism of action of the endothelium‐dependent vasodilatation… Expand

Adenosine receptor agonists and agents enhancing pericellular concentrations of adenosine possess antiinflammatory properties. In… Expand

Nociceptive neurons in the dorsal horn of the cat spinal cord are depressed by vibration applied to the ipsilateral hind limb… Expand