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7H-dibenzo(c,g)carbazole

Known as: 3,4,5,6-Dibenzocarbazole, 7-Aza-7H-dibenzo(c,g)fluorene, 7H-Dibenzo[c,g]carbazole 
A crystalline, carcinogenic aromatic hydrocarbon consisting of five fused rings and produced during the incomplete combustion of organic matter. 7H… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

CarbazolesCarcinogens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
7H-dibenzo[c,g]carbazole metabolism by the mouse and human CYP1 family of enzymes.
Found in tobacco smoke, fossil fuel and other organic combustion products, 7H-dibenzo[c,g]carbazole (DBC) is a potent mouse lung… 
2004
2004
Histopathological and Molecular Changes During Apoptosis Produced by 7H-Dibenzo[c,g]-Carbazole in Mouse Liver
The topical administration of 7H-dibenzo[c,g]carbazole (7H-DBC) at very low but repeated doses causes genotoxic effects such as… 
2002
2002
A metabolic activation mechanism of 7H-dibenzo[c,g]carbazole via o-quinone. Part 2: covalent adducts of 7H-dibenzo[c,g]carbazole-3,4-dione with nucleic acid bases and nucleosides.
7H-dibenzo[c,g]carbazole (DBC) is a potent multispecies, multisite carcinogen present in the environment. The metabolic… 
1997
1997
Synthesis of depurinating DNA adducts formed by one-electron oxidation of 7H-dibenzo[c,g]carbazole and identification of these adducts after activation with rat liver microsomes.
It is hypothesized that 7H-dibenzo[c,g]carbazole (DBC) is metabolically activated by one-electron oxidation in accordance with… 
Review
1996
Review
1996
Comparative carcinogenicity, metabolism, mutagenicity, and DNA binding of 7H-dibenzo[c,g]carbazole and dibenz[a,j]acridine.
Complex mixtures that are produced from the combustion of organic materials have been associated with increased cancer mortality… 
1996
1996
Carcinogenicity, DNA adduct formation and K-ras activation by 7H-dibenzo[c,g]carbazole in strain A/J mouse lung.
N-Heterocyclic polynuclear aromatic hydrocarbons (NHA) are environmental pollutants formed during the combustion of organic… 
1995
1995
Interaction of 7H‐dibenzo[c, g]carbazole and its organspecific derivatives with hepatic mitochondrial and nuclear DNA in the mouse
The recent observation of a high level of adducts in mitochondrial DNA (mtDNA) of cells exposed to chemical carcinogens aroused… 
Highly Cited
1990
Highly Cited
1990
A comparison of DNA adduct formation in white blood cells and internal organs of mice exposed to benzo[a]pyrene, dibenzo[c,g]carbazole, safrole and cigarette smoke condensate.
1987
1987
32P-postlabeling analysis of DNA adduction in mice by synthetic metabolites of the environmental carcinogen, 7H-dibenzo[c,g]carbazole: chromatographic evidence for 3-hydroxy-7H-dibenzo[c,g]carbazole…
The DNA adduction by the environmental carcinogen 7H-dibenzo[c,g]carbazole (DBC) and chemically synthesized 2-OH, 3-OH, and 4-OH… 
1985
1985
Tissue-specific DNA adduct formation in mice treated with the environmental carcinogen, 7H-dibenzo[c,g]carbazole.
Covalent adduction of DNA by chemical agents is commonly thought to be an essential part of the initiation of chemical… 
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