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National Institutes of Health
analogs & derivatives
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Irreversible trapping of the DNA-topoisomerase I covalent complex. Affinity labeling of the camptothecin binding site.
The Journal of biological chemistry
Corpus ID: 24758864
Camptothecin (CPT) binds reversibly to, and thereby stabilizes, the cleavable complex formed between DNA and topoisomerase I. The…
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