7-ketolithocholic acid

The oxidized bile acid 7-oxoLCA (7-oxolithocholic acid), formed primarily by gut micro-organisms, is reduced in human liver to… Expand

Preparation of some biologically important keto bile acids is described. Advantage is taken of the preferential ketalization of 3… Expand

Because ursodeoxycholic and chenodeoxycholic acids are interconverted in humans via 7-ketolithocholic acid, bile acid metabolism… Expand

The formation of ursodeoxycholic acid from chenodeoxycholic acid and the role of 7-ketolithocholic acid as an intermediate in… Expand

The interaction of human serum albumin with twelve bile acids (ba) has been studied by equilibrium dialysis technique using 3H… Expand

Abstract Bile acids are thought to increase choleresis through their osmotic activity. The reported experiments suggest a… Expand

Abstract Bile acids are thought to increase choleresis through their osmotic activity. The reported experiments suggest a… Expand

To define the metabolism of 7-ketolithocholic acid in man, studies were carried out in gallstone patients with normal liver… Expand

Feces from normal subjects and patients with cerebrotendinous xanthomatosis were incubated anaerobically with labeled… Expand

The formation of ursodeoxycholic acid, the 7 beta-hydroxy epimer of chenodeoxycholic acid, was investigated in three subjects… Expand