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7-ketolithocholic acid

Known as: (3 alpha,5 beta)-3-hydroxy-7-oxocholan-24-oic acid, 7-oxolithocholic acid 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (1)

3 alpha-hydroxy-7-keto-5 beta-cholanoate

Broader (2)

Cholagogues and CholereticsLithocholic Acid
analogs & derivatives

Papers overview

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2011
2011
Hepatic reduction of the secondary bile acid 7-oxolithocholic acid is mediated by 11β-hydroxysteroid dehydrogenase 1.
The oxidized bile acid 7-oxoLCA (7-oxolithocholic acid), formed primarily by gut micro-organisms, is reduced in human liver to… 
1991
1991
Selective reduction of oxo bile acids: synthesis of 3 beta-, 7 beta-, and 12 beta-hydroxy bile acids.
Preparation of some biologically important keto bile acids is described. Advantage is taken of the preferential ketalization of 3… 
1990
1990
Ursodeoxycholic acid, chenodeoxycholic acid, and 7-ketolithocholic acid are primary bile acids of the guinea pig.
Guinea pig gallbladder bile contains chenodeoxycholic acid (62 +/- 5%), ursodeoxycholic acid (8 +/- 5%), and 7-ketolithocholic… 
Highly Cited
1983
Highly Cited
1983
Formation of ursodeoxycholic acid from chenodeoxycholic acid in the human colon: studies of the role of 7-ketolithocholic acid as an intermediate.
The formation of ursodeoxycholic acid from chenodeoxycholic acid and the role of 7-ketolithocholic acid as an intermediate in… 
Highly Cited
1982
Highly Cited
1982
Quantitative aspects of the interaction of bile acids with human serum albumin.
The interaction of human serum albumin with twelve bile acids (ba) has been studied by equilibrium dialysis technique using 3H… 
Highly Cited
1982
Highly Cited
1982
Hepatic bile acid uptake: effect of conjugation, hydroxyl and keto groups, and albumin binding.
Highly Cited
1980
Highly Cited
1980
Hypercholeresis induced by ursodeoxycholic acid and 7-ketolithocholic acid in the rat: possible role of bicarbonate transport.
Highly Cited
1980
Highly Cited
1980
Metabolism in man of 7-ketolithocholic acid: precursor of cheno- and ursodeoxycholic acids.
To define the metabolism of 7-ketolithocholic acid in man, studies were carried out in gallstone patients with normal liver… 
Highly Cited
1979
Highly Cited
1979
Transformation of chenodeoxycholic acid and ursodeoxycholic acid by human intestinal bacteria.
Highly Cited
1974
Highly Cited
1974
Increased formation of ursodeoxycholic acid in patients treated with chenodeoxycholic acid.
The formation of ursodeoxycholic acid, the 7 beta-hydroxy epimer of chenodeoxycholic acid, was investigated in three subjects… 
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