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7-ketolithocholic acid

Known as: (3 alpha,5 beta)-3-hydroxy-7-oxocholan-24-oic acid, 7-oxolithocholic acid 
National Institutes of Health

Related topics

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4 relations

Narrower (1)

3 alpha-hydroxy-7-keto-5 beta-cholanoate

Broader (2)

Cholagogues and CholereticsLithocholic Acid
analogs & derivatives

Papers overview

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2014
2014
Preparation of ursodeoxycholic acid by direct electro-reduction of 7-ketolithocholic acid
A novel method of producing ursodeoxycholic acid was developed through direct electro-reduction of 7-ketolithocholic acid in a… 
1991
1991
Selective reduction of oxo bile acids: synthesis of 3 beta-, 7 beta-, and 12 beta-hydroxy bile acids.
Preparation of some biologically important keto bile acids is described. Advantage is taken of the preferential ketalization of 3… 
1990
1990
Ursodeoxycholic acid, chenodeoxycholic acid, and 7-ketolithocholic acid are primary bile acids of the guinea pig.
Guinea pig gallbladder bile contains chenodeoxycholic acid (62 +/- 5%), ursodeoxycholic acid (8 +/- 5%), and 7-ketolithocholic… 
1989
1989
Reduction of 7-ketolithocholic acid by human liver enzyme preparations in vitro.
The formation of chenodeoxycholic and ursodeoxycholic acids from 7-ketolithocholic acid by human liver preparations was examined… 
1987
1987
Oxidation of primary bile acids by a 7 alpha-hydroxysteroid dehydrogenase elaborating Clostridium bifermentans soil isolate.
A gram-positive, rod-shaped anaerobe (strain F-6) was isolated from soil. This organism was identified by cellular morphology as… 
1985
1985
Absorption of 7-ketolithocholic acid in rat jejunum, ileum and colon.
7-Ketolithocholic acid is a bile acid which is formed in the intestine of man by bacterial oxidation of chenodeoxycholic acid and… 
Highly Cited
1983
Highly Cited
1983
Formation of ursodeoxycholic acid from chenodeoxycholic acid in the human colon: studies of the role of 7-ketolithocholic acid as an intermediate.
The formation of ursodeoxycholic acid from chenodeoxycholic acid and the role of 7-ketolithocholic acid as an intermediate in… 
Highly Cited
1980
Highly Cited
1980
Metabolism in man of 7-ketolithocholic acid: precursor of cheno- and ursodeoxycholic acids.
To define the metabolism of 7-ketolithocholic acid in man, studies were carried out in gallstone patients with normal liver… 
1980
1980
Effect of cecum and appendix on 7 alpha-dehydroxylation and 7 beta-epimerization of chenodeoxycholic acid in the rabbit.
The effect of surgical removal of cecum and appendix on bile acid metabolism was studied in the rabbit. Bile acid composition of… 
1975
1975
Bile acids. XLIV, quantitation of bile acids from the bile fistula rat given (4-14C) cholesterol.
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