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7-ketolithocholic acid

Known as: (3 alpha,5 beta)-3-hydroxy-7-oxocholan-24-oic acid, 7-oxolithocholic acid 
 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (1)

3 alpha-hydroxy-7-keto-5 beta-cholanoate

Broader (2)

Cholagogues and CholereticsLithocholic Acid
analogs & derivatives

Papers overview

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2011
2011
Hepatic reduction of the secondary bile acid 7-oxolithocholic acid is mediated by 11β-hydroxysteroid dehydrogenase 1.
The oxidized bile acid 7-oxoLCA (7-oxolithocholic acid), formed primarily by gut micro-organisms, is reduced in human liver to… Expand
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2007
2007
Conversion of 7-ketolithocholic acid to ursodeoxycholic acid by human intestinal anaerobic microorganisms: Interchangeability of chenodeoxycholic acid and ursodeoxycholic acid
SummaryChenodeoxycholic acid, ursodeoxycholic acid and 7-ketolithocholic acid were incubated with human intestinal bacteria… Expand
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1990
1990
Ursodeoxycholic acid, chenodeoxycholic acid, and 7-ketolithocholic acid are primary bile acids of the guinea pig.
Guinea pig gallbladder bile contains chenodeoxycholic acid (62 +/- 5%), ursodeoxycholic acid (8 +/- 5%), and 7-ketolithocholic… Expand
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1986
1986
Ursodeoxycholic acid, 7-ketolithocholic acid, and chenodeoxycholic acid are primary bile acids of the nutria (Myocastor coypus).
Because ursodeoxycholic and chenodeoxycholic acids are interconverted in humans via 7-ketolithocholic acid, bile acid metabolism… Expand
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1983
1983
Formation of ursodeoxycholic acid from chenodeoxycholic acid in the human colon: studies of the role of 7-ketolithocholic acid as an intermediate.
The formation of ursodeoxycholic acid from chenodeoxycholic acid and the role of 7-ketolithocholic acid as an intermediate in… Expand
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Highly Cited
1982
Highly Cited
1982
Quantitative aspects of the interaction of bile acids with human serum albumin.
The interaction of human serum albumin with twelve bile acids (ba) has been studied by equilibrium dialysis technique using 3H… Expand
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1980
1980
Hypercholeresis induced by ursodeoxycholic acid and 7-ketolithocholic acid in the rat: possible role of bicarbonate transport.
Abstract Bile acids are thought to increase choleresis through their osmotic activity. The reported experiments suggest a… Expand
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1980
1980
Metabolism in man of 7-ketolithocholic acid: precursor of cheno- and ursodeoxycholic acids.
To define the metabolism of 7-ketolithocholic acid in man, studies were carried out in gallstone patients with normal liver… Expand
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1979
1979
Transformation of chenodeoxycholic acid and ursodeoxycholic acid by human intestinal bacteria.
Feces from normal subjects and patients with cerebrotendinous xanthomatosis were incubated anaerobically with labeled… Expand
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1974
1974
Increased formation of ursodeoxycholic acid in patients treated with chenodeoxycholic acid.
The formation of ursodeoxycholic acid, the 7 beta-hydroxy epimer of chenodeoxycholic acid, was investigated in three subjects… Expand
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