7-hydroxyloxapine

Known as: Dibenz(b,f)(1,4)oxazepin-7-ol, 2-chloro-11-(4-methyl-1-piperazinyl)- 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2017
0119792017

Papers overview

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2017
2017
Loxapine is an antipsychotic medication used for the treatment of schizophrenia. In vivo, loxapine is metabolized to multiple… (More)
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2011
2011
In vitro studies were conducted to identify the hepatic cytochrome P450 (CYP) enzymes responsible for the oxidative metabolism of… (More)
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1999
1999
Two antipsychotic drugs (clozapine and loxapine) and six metabolites, N-demethylclozapine, clozapine N-oxide, N-demethylloxapine… (More)
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1993
1993
Loxapine is a drug which is used in the treatment of psychotic disorders. The drug is extensively biotransformed in humans to… (More)
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1991
1991
Loxapine, its N-demethylated metabolite amoxapine, and their 7- and 8-hydroxy metabolites were determined simultaneously in… (More)
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1979
1979
The effects of loxapine and its hydroxylated metabolites 7-hydroxyloxapine and 8-hydroxyloxapine on 3H-spiroperidol binding to… (More)
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