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7-hydroxychlorpromazine

Known as: 8-chloro-10-(3-(dimethylamino)propyl)-10H- phenothiazin-3-ol 
 

Topic mentions per year

Topic mentions per year

1963-2004
012319632004

Related topics

Related topics

1 relation

Broader (1)

Chlorpromazine

Related mentions per year

Related mentions per year

1953-2018
1960198020002020
7-hydroxychlorpromazine
Chlorpromazine

Papers overview

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1996
1996
Quinidine inhibits the 7-hydroxylation of chlorpromazine in extensive metabolisers of debrisoquine
Quinidine is a potent inhibitor of CYP2D6 (debrisoquine 4-hydroxylase). Its effect on the disposition of chlorpromazine was… (More)
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1996
1996
Response in chronic schizophrenia correlated with chlorpromazine, 7-OH-chlorpromazine and chlorpromazine sulfoxide levels.
The relationship between chlorpromazine, six of its metabolites and therapeutic response in chronic schizophrenic patients was… (More)
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1996
1996
Biotransformation of chlorpromazine and methdilazine by Cunninghamella elegans.
When tested as a microbial model for mammalian drug metabolism, the filamentous fungus Cunninghamella elegans metabolized… (More)
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1988
1988
Alpha-2A and alpha-2B adrenergic receptor subtypes: antagonist binding in tissues and cell lines containing only one subtype.
The affinities of 34 adrenergic antagonists for alpha-2 adrenergic receptors were determined from homogenate radioligand binding… (More)
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1985
1985
A comparison of two radioimmunoassays for 7-hydroxychlorpromazine: rabbit polyclonal antibodies vs. mouse monoclonal antibodies.
Two radioimmunoassays (RIAs) were developed for 7-hydroxychlorpromazine (7-OHCPZ), which is a pharmacologically active… (More)
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1982
1982
The presence of 7-hydroxychlorpromazine in CSF of chlorpromazine-treated patients
7-Hydroxychlorpromazine (7-OHCPZ) has been identified and quantified in CSF from chlorpromazine (CPZ)-treated schizophrenic… (More)
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1978
1978
Chemical and electrochemical oxidation of 7-hydroxychlorpromazine.
The oxidation of 7-hydroxychlorpromazine, a process associated with several side effects of chlorpromazine therapy, was examined… (More)
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1977
1977
Studies on the glucuronidation of 7-hydroxychlorpromazine in vitro.
The glucuronide of 7-hydroxychlorpromazine (CPOH), formed by incubation with hepatic microsomes and UDP-[U-14C]glucuronic acid… (More)
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1974
1974
The relationship of plasma chlorpromazine to its 7-hydroxy and sulphoxide metabolites in a large population of chronic schizophrenics.
1 Blood samples were obtained from eighty-six chronic schizophrenics receiving a wide range of oral doses of chlorpromazine… (More)
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1973
1973
The possible role of metabolites in therapeutic response to chlorpromazine treatment
Eight male adult schizophrenic patients undergoing chronic treatment with chlorpromazine were investigated. Clinical assessments… (More)
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